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HAMAP rule MF_01906

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General rule information [?]

Accession MF_01906
Dates 28-NOV-2007 (Created)
19-NOV-2019 (Last updated, Version 13)
Name 3HBOH
Scope(s) Bacteria
Template(s) O05690 (HBOH1_RALPI); Q9X6X9 (HBOH2_RALPI); Q0K9H3 (HBOH_CUPNH); [ Recover all ]
Triggered by HAMAP; MF_01906 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier HBOH
case <Feature:Signal==1>
Protein name RecName: Full=D-(-)-3-hydroxybutyrate oligomer hydrolase;
                 Short=3HB-oligomer hydrolase;
                 Flags: Precursor;
Protein name RecName: Full=D-(-)-3-hydroxybutyrate oligomer hydrolase;
                 Short=3HB-oligomer hydrolase;
end case

Comments [?]

FUNCTIONParticipates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB- oligomers) into 3HB-monomers.
CATALYTIC ACTIVITY Reaction=(3R)-hydroxybutanoate dimer + H2O = 2 (R)-3-hydroxybutanoate + H(+); Xref=Rhea:RHEA:10172, ChEBI:CHEBI:10979, ChEBI:CHEBI:10983, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378; EC=;
PATHWAYLipid metabolism; butanoate metabolism.
case <Feature:Signal==1>
end case
SIMILARITYBelongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.

Keywords [?]

case <Feature:Signal==1>
end case

Gene Ontology [?]

GO:0047989; Molecular function:hydroxybutyrate-dimer hydrolase activity
GO:0019605; Biological process:butyrate metabolic process

Cross-references [?]

Pfam PF10605; 3HBOH; 1;
PIRSF PIRSF011409; HObutyrate_olig_hydrol; 1;
General Signal; -; 0-1;

Features [?]

Key From To Description Tag Condition FTGroup
ACT_SITE 320 320 /note="Charge relay system" S

Additional information [?]

Size range 695-750 amino acids
Related rules None
Fusion Nter: None Cter: None
Comments HBOH_CUPNH is an atypical member since it has a predicted signal sequence but is intracellular.

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