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Annotation rule MF_01906
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General rule information [?]

Accession MF_01906
Dates 28-NOV-2007 (Created)
19-NOV-2019 (Last updated, Version 13)
Name 3HBOH
Scope
Bacteria; Betaproteobacteria
Bacteria; Alteromonadaceae
Templates O05690 (HBOH1_RALPI); Q9X6X9 (HBOH2_RALPI); Q0K9H3 (HBOH_CUPNH): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
HBOH
case <Feature:Signal==1>
Protein name
RecName: Full=D-(-)-3-hydroxybutyrate oligomer hydrolase;
Short=3HB-oligomer hydrolase;
Short=3HBOH;
EC 3.1.1.22;
Flags: Precursor;
else
Protein name
RecName: Full=D-(-)-3-hydroxybutyrate oligomer hydrolase;
Short=3HB-oligomer hydrolase;
Short=3HBOH;
EC 3.1.1.22;
end case

Comments [?]

Function Participates in the degradation of poly-3-hydroxybutyrate (PHB). It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
Catalytic activity RHEA:10172: (3R)-hydroxybutanoate dimer + H2O = 2 (R)-3-hydroxybutanoate + H(+)
EC 3.1.1.22
Pathway Lipid metabolism; butanoate metabolism.
case <Feature:Signal==1>
Subcellular location Secreted.
end case
Similarity Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.

Keywords [?]

Hydrolase
case <Feature:Signal==1>
Secreted
Signal
end case

Gene Ontology [?]

GO:0047989; Molecular function: hydroxybutyrate-dimer hydrolase activity.
GO:0019605; Biological process: butyrate metabolic process.

Cross-references [?]

Pfam PF10605; 3HBOH; 1;
PIRSF PIRSF011409; HObutyrate_olig_hydrol; 1;

Computed features [?]

General Signal; -; 0-1; trigger=yes;

Features [?]

From: HBOH_CUPNH (Q0K9H3)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     320     320       Charge relay system     S  

Additional information [?]

Size range 695-750 amino acids
Related rules None
Fusion None
Comments HBOH_CUPNH is an atypical member since it has a predicted signal sequence but is intracellular.


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