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HAMAP rule MF_01912

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General rule information [?]

Accession MF_01912
Dates 31-MAR-2014 (Created)
5-JUL-2023 (Last updated, Version 8)
Name SFP_aldolase
Scope(s) Bacteria
Enterobacterales
Template(s) P32141 (SQUT_ECOLI); Q9L7R9 (SQUT_SALTY); [ Recover all ]
Triggered by HAMAP; MF_01912 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier SQUT
Protein name RecName: Full=Sulfofructosephosphate aldolase;
                 Short=SFP aldolase;
                 EC=4.1.2.57;

Comments [?]

FUNCTIONCleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).
CATALYTIC ACTIVITY Reaction=6-deoxy-6-sulfo-D-fructose 1-phosphate = (2S)-3- sulfolactaldehyde + dihydroxyacetone phosphate; Xref=Rhea:RHEA:40515, ChEBI:CHEBI:57642, ChEBI:CHEBI:77134, ChEBI:CHEBI:90109; EC=4.1.2.57; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:40516;
SUBUNITHomotetramer.
SIMILARITYBelongs to the aldolase LacD family.

Keywords [?]


Gene Ontology [?]

GO:0061595; Molecular function:6-deoxy-6-sulfofructose-1-phosphate aldolase activity
GO:1902777; Biological process:6-sulfoquinovose(1-) catabolic process

Cross-references [?]

Pfam PF01791; DeoC; 1;
PIRSF PIRSF037840; Aldolase_YihT; 1;

Features [?]

From: SQUT_SALTY (Q9L7R9)
Key From To Description Tag Condition FTGroup
ACT_SITE 193 193 /note="Schiff-base intermediate with substrate" K

Additional information [?]

Size range 270-305 amino acids
Related rules None
Fusion Nter: None Cter: None



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