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HAMAP rule MF_01935

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General rule information [?]

Accession MF_01935
Dates 15-OCT-2014 (Created)
1-JUN-2023 (Last updated, Version 7)
Name MenF
Scope(s) Bacteria
Template(s) P38051 (MENF_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_01935 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MENF
Protein name RecName: Full=Isochorismate synthase MenF;
AltName: Full=Isochorismate mutase;
Gene name Name=menF;

Comments [?]

FUNCTIONCatalyzes the conversion of chorismate to isochorismate.
CATALYTIC ACTIVITY Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985, ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=;
case <FTGroup:1>
COFACTOR Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
end case
PATHWAYQuinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 1/7.
PATHWAYQuinol/quinone metabolism; menaquinone biosynthesis.
SIMILARITYBelongs to the isochorismate synthase family.

Keywords [?]

Gene Ontology [?]

GO:0008909; Molecular function:isochorismate synthase activity
case <FTGroup:1>
GO:0000287; Molecular function:magnesium ion binding
end case
GO:0009234; Biological process:menaquinone biosynthetic process

Cross-references [?]

Pfam PF00425; Chorismate_bind; 1;
NCBIfam TIGR00543; isochor_syn; 1;

Features [?]

From: MENF_ECOLI (P38051)
Key From To Description Tag Condition FTGroup
ACT_SITE 190 190 /note="Proton acceptor" K
ACT_SITE 240 240 /note="Proton donor" E
BINDING 284 284 /ligand="Mg(2+)"
E 1
BINDING 416 416 /ligand="Mg(2+)"
E 1

Additional information [?]

Size range 385-470 amino acids
Related rules None
Fusion Nter: None Cter: None

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