Home  |  Contact
Annotation rule MF_01943
Send feedback

General rule information [?]

Accession MF_01943
Dates 11-DEC-2014 (Created)
19-NOV-2019 (Last updated, Version 6)
Name Lipid_A_LpxP
Scope
Bacteria; Enterobacterales
Template P0ACV2 (LPXP_ECOLI)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
LPXP
Protein name
RecName: Full=Lipid A biosynthesis palmitoleoyltransferase;
EC 2.3.1.242;
AltName: Full=Kdo(2)-lipid IV(A) palmitoleoyltransferase;
Gene name
lpxP

Comments [?]

Function Catalyzes the transfer of palmitoleate from palmitoleoyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(palmitoleoyl)-lipid IV(A).
Catalytic activity RHEA:44012: (9Z)-hexadecenoyl-[ACP] + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA = (9Z)-hexadecenoyl-(Kdo)2-lipid IVA + holo-[ACP]
EC 2.3.1.242
Pathway Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.
Subcellular location Cell inner membrane; Single-pass membrane protein.
Similarity Belongs to the LpxL/LpxM/LpxP family. LpxP subfamily.

Keywords [?]


Gene Ontology [?]

GO:0008951; Molecular function: palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity.
GO:0036104; Biological process: Kdo2-lipid A biosynthetic process.
GO:0005887; Cellular component: integral component of plasma membrane.

Cross-references [?]

Pfam PF03279; Lip_A_acyltrans; 1;
TIGRFAMs TIGR02207; lipid_A_htrB; 1;
PIRSF PIRSF026649; MsbB; 1;

Computed features [?]

General Transmembrane; -; 1; trigger=yes;

Features [?]

From: LPXP_ECOLI (P0ACV2)
Key     From     To       Description   Tag   Condition   FTGroup
MOTIF     132     137       HXXXXD motif     H-x-x-x-x-[DE]  

Additional information [?]

Size range 302-340 amino acids
Related rules MF_01942 (LPXL)
Fusion None