HAMAP rule MF_01947

General rule information [?]

Accession	MF_01947
Dates	15-JAN-2015 (Created) 19-NOV-2019 (Last updated, Version 3)

Name	Aminopropyltransf_BpsA

Scope

Bacteria

Archaea

Template

Q5JIZ3 (BPSA_THEKO)

Triggered by

HAMAP; MF_01947 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

BPSA

Protein name

RecName:		Full=N(4)-bis(aminopropyl)spermidine synthase;
		EC 2.5.1.128;
AltName:		Full=Branched-chain polyamine synthase A;

Gene name

bpsA

Comments [?]

Function	Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
Catalytic activity	RHEA:44132: 2 S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = 2 H(+) + N(4)-bis(aminopropyl)spermidine + 2 S-methyl-5'-thioadenosine EC 2.5.1.128
Pathway	Amine and polyamine biosynthesis.
Subcellular location	Cytoplasm.
Similarity	Belongs to the branched-chain polyamine synthase family.

Keywords [?]

Cytoplasm
Polyamine biosynthesis
Transferase

Gene Ontology [?]

GO:0016765; Molecular function: transferase activity, transferring alkyl or aryl (other than methyl) groups.
GO:0006596; Biological process: polyamine biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam	PF01861; DUF43; 1;
PIRSF	PIRSF005895; UCP005895_mtase; 1;

Additional information [?]

Size range	320-375 amino acids
Related rules	None
Fusion	None

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