HAMAP rule MF_01947

General rule information [?]

Accession	MF_01947
Dates	15-JAN-2015 (Created) 3-SEP-2024 (Last updated, Version 4)
Name	Aminopropyltransf_BpsA
Scope(s)	Bacteria Archaea
Template(s)	Q5JIZ3 (BPSA_THEKO); [ Recover all ]
Triggered by	HAMAP; MF_01947 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	BPSA
Protein name	RecName: Full=N(4)-bis(aminopropyl)spermidine synthase; EC=2.5.1.128; AltName: Full=Branched-chain polyamine synthase A;
Gene name	Name=bpsA;

Comments [?]

FUNCTION	Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
CATALYTIC ACTIVITY	Reaction=2 S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = N(4)-bis(aminopropyl)spermidine + 2 S-methyl-5'-thioadenosine + 2 H(+); Xref=Rhea:RHEA:44132, ChEBI:CHEBI:15378, ChEBI:CHEBI:17509, ChEBI:CHEBI:57443, ChEBI:CHEBI:57834, ChEBI:CHEBI:82771; EC=2.5.1.128;
PATHWAY	Amine and polyamine biosynthesis.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the branched-chain polyamine synthase family.

Keywords [?]

Gene Ontology [?]

GO:0016765; Molecular function:transferase activity, transferring alkyl or aryl (other than methyl) groups

GO:0006596; Biological process:polyamine biosynthetic process

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF01861; DUF43; 1;
PIRSF	PIRSF005895; UCP005895_mtase; 1;

Features [?]

Additional information [?]