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HAMAP rule MF_01954

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General rule information [?]

Accession MF_01954
Dates 10-APR-2006 (Created)
1-JUN-2023 (Last updated, Version 22)
Name Urease_beta
Scope(s) Bacteria
Template(s) P41021 (URE2_SPOPA); P18315 (URE2_KLEAE); [ Recover all ]
Triggered by HAMAP; MF_01954 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier URE2
Protein name RecName: Full=Urease subunit beta;
AltName: Full=Urea amidohydrolase subunit beta;
Gene name Name=ureB;

Comments [?]

CATALYTIC ACTIVITY Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+); Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938; EC=;
PATHWAYNitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.
SUBUNITHeterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.
SIMILARITYBelongs to the urease beta subunit family.

Keywords [?]

Gene Ontology [?]

GO:0009039; Molecular function:urease activity
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF00699; Urease_beta; 1;
NCBIfam TIGR00192; Urease_beta; 1;

Features [?]

Additional information [?]

Size range 101-164 amino acids
Related rules MF_01955
Fusion Nter: None Cter: None
Comments Fused with the urease gamma subunit in a number of bacterial species and in SULTO

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