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Annotation rule MF_01955
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General rule information [?]

Accession MF_01955
Dates 10-APR-2006 (Created)
19-NOV-2019 (Last updated, Version 18)
Name Urease_beta_gamma
Scope
Bacteria; Streptomycetales
Bacteria; Deinococcales
Bacteria; Campylobacterales
Bacteria; Pseudomonadaceae
Archaea; Sulfolobales
Template P14916 (URE23_HELPY)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
URE23
case <OC:Campylobacterales>
Protein name
RecName: Full=Urease subunit alpha;
EC 3.5.1.5;
AltName: Full=Urea amidohydrolase subunit alpha;
Gene name
ureA
else case not <OC:Campylobacterales>
Protein name
RecName: Full=Urease subunit gamma/beta;
EC 3.5.1.5;
AltName: Full=Urea amidohydrolase subunit gamma/beta;
Gene name
ureAB
end case

Comments [?]

Catalytic activity RHEA:20557: 2 H(+) + H2O + urea = CO2 + 2 NH4(+)
EC 3.5.1.5
Pathway Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1.
case <OC:Campylobacterales>
Subunit Heterohexamer of 3 UreA (alpha) and 3 UreB (beta) subunits.
else case not <OC:Campylobacterales>
Subunit Heterohexamer of 3 UreC (alpha) and 3 UreAB (gamma/beta) subunits.
end case
Subcellular location Cytoplasm.
Similarity In the N-terminal section; belongs to the urease gamma subunit family.
In the C-terminal section; belongs to the urease beta subunit family.
case <OC:Campylobacterales>
Caution The orthologous protein is known as the gamma/beta subunit (UreAB) in most other bacteria.
end case

Keywords [?]

Cytoplasm
Hydrolase

Gene Ontology [?]

GO:0009039; Molecular function: urease activity.
GO:0019627; Biological process: urea metabolic process.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00699; Urease_beta; 1;
PF00547; Urease_gamma; 1;
TIGRFAMs TIGR00192; Urease_beta; 1;
TIGR00193; Urease_gam; 1;

Features [?]

From: URE23_HELPY (P14916)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     Nter     102       Urease gamma        
REGION     103     Cter       Urease beta        

Additional information [?]

Size range 219-238 amino acids
Related rules MF_00739 (URE3); MF_01954 (URE2)
Fusion None


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