 |
|
Annotation rule MF_01959 |
General rule information
[?]
Accession |
MF_01959 |
Dates |
12-MAY-2006 (Created) 19-NOV-2019 (Last updated, Version 24) |
Scope |
Bacteria; Deinococci
Bacteria; Proteobacteria |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Protein name |
RecName:
|
Full=Cytochrome c-type biogenesis protein CcmE;
|
AltName:
|
Full=Cytochrome c maturation protein E;
|
AltName:
|
Full=Heme chaperone CcmE;
|
|
Function |
Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. |
case not defined <Property:Membrane> or <Property:Membrane=1>
Subcellular location |
Cell membrane; Single-pass type II membrane protein. |
else case <Property:Membrane=2>
Subcellular location |
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side. |
end case
Similarity |
Belongs to the CcmE/CycJ family. |
case defined <Property:Membrane> and <Property:Membrane=2>
end case
GO:0017003; Biological process: protein-heme linkage.
GO:0005886; Cellular component: plasma membrane.
From: CCME_ECOLI (P69490) |
Key
|
|
From
|
|
To
|
|
Description
|
|
Tag
|
|
Condition
|
|
FTGroup
|
TOPO_DOM
|
|
Nter
|
|
8
|
|
Cytoplasmic
|
|
|
|
|
|
|
TRANSMEM
|
|
9
|
|
29
|
|
Helical; Signal-anchor for type II membrane protein
|
|
|
|
|
|
|
case not defined <Property:Membrane> or <Property:Membrane=1>
TOPO_DOM
|
|
30
|
|
Cter
|
|
Extracellular
|
|
|
|
|
|
|
end case
case defined <Property:Membrane> and <Property:Membrane=2>
TOPO_DOM
|
|
30
|
|
Cter
|
|
Periplasmic
|
|
|
|
|
|
|
end case
METAL
|
|
134
|
|
134
|
|
Iron (heme axial ligand)
|
|
|
|
Y
|
|
|
BINDING
|
|
130
|
|
130
|
|
Heme (covalent; via pros nitrogen)
|
|
|
|
H
|
|
|
Additional information
[?]
Size range |
128-181 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
In SALCH, the duplicated copy ccmE2 is fused to ccmA2, however, important parts of the proteins are missing and it is therefore probably not functional. May be a pseudogene. |