![]() |
|
Annotation rule MF_01960 |
Accession | MF_01960 |
Dates | 6-SEP-2006 (Created) 19-NOV-2019 (Last updated, Version 12) |
Name | D_aminopeptidase |
Scope | Bacteria; Alphaproteobacteria |
Template | Q9ZBA9 (DAP_OCHAN) |
Triggered by |
Identifier |
|
Protein name |
|
Gene name |
|
Function | Hydrolyzes N-terminal residues in D-amino acid-containing peptides. |
Catalytic activity | Reaction=Release of an N-terminal D-amino acid from a peptide, Xaa-|-Yaa-, in which Xaa is preferably D-Ala, D-Ser or D-Thr. D-amino acid amides and methyl esters also are hydrolyzed, as is glycine amide.; EC=3.4.11.19; |
Activity regulation | Inhibited by beta-lactam compounds such as 6-aminopenicillic acid, 7-aminocephalosporanic acid, benzylpenicillin and ampicillin. Inhibited by p-chloromercuribenzoate. |
Subunit | Homodimer. |
Similarity | Belongs to the peptidase S12 family. |
From: DAP_OCHAN (Q9ZBA9) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION | 477 | 487 | Important for specificity | |||||||||
ACT_SITE | 62 | 62 | Nucleophile | S | ||||||||
ACT_SITE | 65 | 65 | Proton donor/acceptor | K | ||||||||
BINDING | 481 | 481 | Substrate | D |
Size range | 516-525 amino acids |
Related rules | None |
Fusion | None |