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HAMAP rule MF_01983

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General rule information [?]

Accession MF_01983
Dates 1-SEP-2015 (Created)
1-JUN-2023 (Last updated, Version 8)
Name UbiD_FDC
Templates Q9I6N5 (P2CDC_PSEAE); Q03034 (FDC1_YEAST): [Recover all]
case <OC:Bacteria>
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Pyrrole-2-carboxylic acid decarboxylase;
Short=P2C decarboxylase;

Comments [?]

Function Catalyzes the prenyl-FMN-dependent decarboxylation of pyrrole-2-carboxylate (P2C). Can also catalyze the carboxylation of pyrrole in the presence of elevated concentrations of CO(2) or bicarbonate.
Catalytic activity RHEA:31375: H(+) + pyrrole-2-carboxylate = 1H-pyrrole + CO2
RHEA:31379: H2O + pyrrole-2-carboxylate = 1H-pyrrole + hydrogencarbonate
Cofactor prenyl-FMN
Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
Note: Binds 1 Mn(2+) per subunit.
Note: Binds 1 K(+) per subunit.
Subunit Homodimer.
Similarity Belongs to the UbiD family. UbiD-like/FDC subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016831; Molecular function: carboxy-lyase activity.

Cross-references [?]

Pfam PF01977; UbiD; 1;
NCBIfam TIGR00148; TIGR00148; 1;

Features [?]

From: P2CDC_PSEAE (Q9I6N5)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     278     278       Proton donor     E  
BINDING     166     166       /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103     W  
BINDING     168     168       /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746     V  
BINDING     170     170       /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746     R  
BINDING     187     187       /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746     Q  
BINDING     188     188       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035     H  
BINDING     188     188       /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746     H  
BINDING     218     218       /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103     A  
BINDING     219     219       /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103     A  
BINDING     221     221       /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103     M  
BINDING     229     229       /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103     E  
BINDING     229     229       /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035     E  
BINDING     229     229       /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746     E  
BINDING     386     386       /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746     H  

Additional information [?]

Size range 485-507 amino acids
Related rules None
Fusion None