HAMAP rule MF_01983

General rule information [?]

Accession	MF_01983
Dates	1-SEP-2015 (Created) 1-JUN-2023 (Last updated, Version 8)

Name

UbiD_FDC

Scope

Bacteria

Templates

Q9I6N5 (P2CDC_PSEAE); Q03034 (FDC1_YEAST): [Recover all]

case <OC:Bacteria>

Triggered by

end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

P2CDC

Protein name

RecName:		Full=Pyrrole-2-carboxylic acid decarboxylase;
		Short=P2C decarboxylase;
		EC 4.1.1.93;

Comments [?]

Function	Catalyzes the prenyl-FMN-dependent decarboxylation of pyrrole-2-carboxylate (P2C). Can also catalyze the carboxylation of pyrrole in the presence of elevated concentrations of CO(2) or bicarbonate.
Catalytic activity	RHEA:31375: H(+) + pyrrole-2-carboxylate = 1H-pyrrole + CO2 EC 4.1.1.93
	RHEA:31379: H2O + pyrrole-2-carboxylate = 1H-pyrrole + hydrogencarbonate EC 4.1.1.93
Cofactor	prenyl-FMN Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
	Mn(2+) Note: Binds 1 Mn(2+) per subunit.
	K(+) Note: Binds 1 K(+) per subunit.
Subunit	Homodimer.
Similarity	Belongs to the UbiD family. UbiD-like/FDC subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016831; Molecular function: carboxy-lyase activity.

Cross-references [?]

Pfam	PF01977; UbiD; 1;
NCBIfam	TIGR00148; TIGR00148; 1;

Features [?]

From: P2CDC_PSEAE (Q9I6N5)

Key From To Description Tag Condition FTGroup

ACT_SITE 278 278 Proton donor E

BINDING 166 166 /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103 W

BINDING 168 168 /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746 V

BINDING 170 170 /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746 R

BINDING 187 187 /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746 Q

BINDING 188 188 /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035 H

BINDING 188 188 /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746 H

BINDING 218 218 /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103 A

BINDING 219 219 /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103 A

BINDING 221 221 /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103 M

BINDING 229 229 /ligand="K(+)" /ligand_id="ChEBI:CHEBI:29103 E

BINDING 229 229 /ligand="Mn(2+)" /ligand_id="ChEBI:CHEBI:29035 E

BINDING 229 229 /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746 E

BINDING 386 386 /ligand="prenyl-FMN" /ligand_id="ChEBI:CHEBI:87746 H

Additional information [?]