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HAMAP rule MF_02000

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General rule information [?]

Accession MF_02000
Dates 28-JUL-2005 (Created)
20-NOV-2019 (Last updated, Version 15)
Name HSP20_IbpA
Bacteria; Enterobacterales
Template P0C054 (IBPA_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Small heat shock protein IbpA;
AltName: Full=16 kDa heat shock protein A;
Gene name

Comments [?]

Function Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent.
Subunit Monomer. Forms homomultimers of about 100-150 subunits at optimal growth temperatures. Conformation changes to monomers at high temperatures or high ionic concentrations.
Subcellular location Cytoplasm.
Similarity Belongs to the small heat shock protein (HSP20) family.

Keywords [?]

Gene Ontology [?]

GO:0050821; Biological process: protein stabilization.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF00011; HSP20; 1;
PROSITE PS01031; SHSP; 1; trigger=PRU00285;

Additional information [?]

Size range 130-160 amino acids
Related rules None
Fusion None