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Annotation rule MF_02010
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General rule information [?]

Accession MF_02010
Dates 2-MAY-2008 (Created)
20-NOV-2019 (Last updated, Version 11)
Name IraD
Scope
Bacteria; Enterobacteriaceae
Template P39375 (IRAD_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
IRAD
Protein name
RecName: Full=Anti-adapter protein IraD;
Gene name
iraD

Comments [?]

Function Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
Subunit Interacts with RssB.
Subcellular location Cytoplasm.
Similarity Belongs to the GpW/Gp25 family. IraD subfamily.

Keywords [?]

Cytoplasm
Stress response

Gene Ontology [?]

GO:0034599; Biological process: cellular response to oxidative stress.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

Pfam PF04965; GPW_gp25; 1;

Additional information [?]

Size range 126-130 amino acids
Related rules None
Fusion None


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