HAMAP rule MF_02010

General rule information [?]

Accession	MF_02010
Dates	2-MAY-2008 (Created) 20-NOV-2019 (Last updated, Version 11)
Name	IraD
Scope(s)	Bacteria Enterobacteriaceae
Template(s)	P39375 (IRAD_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_02010 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	IRAD
Protein name	RecName: Full=Anti-adapter protein IraD;
Gene name	Name=iraD;

Comments [?]

FUNCTION	Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
SUBUNIT	Interacts with RssB.
SUBCELLULAR LOCATION	Cytoplasm.
SIMILARITY	Belongs to the GpW/Gp25 family. IraD subfamily.

Keywords [?]

Gene Ontology [?]

GO:0034599; Biological process:cellular response to oxidative stress

GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam	PF04965; GPW_gp25; 1;

Features [?]

Additional information [?]