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Annotation rule MF_02010 |
Accession | MF_02010 |
Dates | 2-MAY-2008 (Created) 20-NOV-2019 (Last updated, Version 11) |
Name | IraD |
Scope | Bacteria; Enterobacteriaceae |
Template | P39375 (IRAD_ECOLI) |
Triggered by |
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Protein name |
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Gene name |
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Function | Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway. |
Subunit | Interacts with RssB. |
Subcellular location | Cytoplasm. |
Similarity | Belongs to the GpW/Gp25 family. IraD subfamily. |
Pfam | PF04965; GPW_gp25; 1; |
Size range | 126-130 amino acids |
Related rules | None |
Fusion | None |