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HAMAP rule MF_02010

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General rule information [?]

Accession MF_02010
Dates 2-MAY-2008 (Created)
20-NOV-2019 (Last updated, Version 11)
Name IraD
Scope(s) Bacteria
Template(s) P39375 (IRAD_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02010 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier IRAD
Protein name RecName: Full=Anti-adapter protein IraD;
Gene name Name=iraD;

Comments [?]

FUNCTIONInhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
SUBUNITInteracts with RssB.
SIMILARITYBelongs to the GpW/Gp25 family. IraD subfamily.

Keywords [?]

Gene Ontology [?]

GO:0034599; Biological process:cellular response to oxidative stress
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Pfam PF04965; GPW_gp25; 1;

Features [?]

Additional information [?]

Size range 126-130 amino acids
Related rules None
Fusion Nter: None Cter: None

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