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Annotation rule MF_02012 |
Accession | MF_02012 |
Dates | 27-JUN-2008 (Created) 20-NOV-2019 (Last updated, Version 9) |
Name | ZapA_type1 |
Scope | Bacteria; Gammaproteobacteria |
Templates | P0ADS2 (ZAPA_ECOLI); Q9HTW3 (ZAPA_PSEAE): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. |
Subunit | Homodimer. Interacts with FtsZ. |
Subcellular location | Cytoplasm. Note=Localizes at mid-cell. |
Similarity | Belongs to the ZapA family. Type 1 subfamily. |
Pfam | PF05164; ZapA; 1; |
General | Coiled_coil; -; 1-unlimited; trigger=yes; |
Size range | 104-109 amino acids |
Related rules | None |
Fusion | None |
Comments | Due to the high divergence of ZapA sequences, this family includes mostly members from the enterobacteria. There is a 3D-structure available for ZapA from Pseudomonas aeruginosa; this protein is not a member of this family though it probably has the same function; the information derived from the structure was included in this rule. |