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Annotation rule MF_02012
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General rule information [?]

Accession MF_02012
Dates 27-JUN-2008 (Created)
20-NOV-2019 (Last updated, Version 9)
Name ZapA_type1
Scope
Bacteria; Gammaproteobacteria
Templates P0ADS2 (ZAPA_ECOLI); Q9HTW3 (ZAPA_PSEAE): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ZAPA
Protein name
RecName: Full=Cell division protein ZapA;
AltName: Full=Z ring-associated protein ZapA;
Gene name
zapA

Comments [?]

Function Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
Subunit Homodimer. Interacts with FtsZ.
Subcellular location Cytoplasm. Note=Localizes at mid-cell.
Similarity Belongs to the ZapA family. Type 1 subfamily.

Keywords [?]

Cell cycle
Cell division
Coiled coil
Cytoplasm
Septation

Gene Ontology [?]

GO:0005886; Cellular component: plasma membrane.
GO:0051301; Biological process: cell division.
GO:0090529; Biological process: cell septum assembly.

Cross-references [?]

Pfam PF05164; ZapA; 1;

Computed features [?]

General Coiled_coil; -; 1-unlimited; trigger=yes;

Additional information [?]

Size range 104-109 amino acids
Related rules None
Fusion None
Comments Due to the high divergence of ZapA sequences, this family includes mostly members from the enterobacteria. There is a 3D-structure available for ZapA from Pseudomonas aeruginosa; this protein is not a member of this family though it probably has the same function; the information derived from the structure was included in this rule.


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