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HAMAP rule MF_02015

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General rule information [?]

Accession MF_02015
Dates 4-JUL-2008 (Created)
1-JUN-2023 (Last updated, Version 10)
Name ParB_Noc
Scope(s) Bacteria
Template(s) P37524 (NOC_BACSU); [ Recover all ]
Triggered by HAMAP; MF_02015 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier NOC
Protein name RecName: Full=Nucleoid occlusion protein;
Gene name Name=noc;

Comments [?]

FUNCTIONEffects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage.
SUBCELLULAR LOCATIONCytoplasm, nucleoid.
SIMILARITYBelongs to the ParB family.

Keywords [?]

Gene Ontology [?]

GO:0005737; Cellular component:cytoplasm
GO:0003677; Molecular function:DNA binding
GO:0051301; Biological process:cell division
GO:0090529; Biological process:cell septum assembly

Cross-references [?]

Pfam PF02195; ParBc; 1;
NCBIfam TIGR00180; ParB_part; 1;

Features [?]

From: NOC_BACSU (P37524)
Key From To Description Tag Condition FTGroup
DNA_BIND 148 167 /note="H-T-H motif"

Additional information [?]

Size range 281-298 amino acids
Related rules None
Fusion Nter: None Cter: None

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