HAMAP rule MF_02015
General rule information
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Accession | MF_02015 |
Dates | 4-JUL-2008 (Created)
1-JUN-2023 (Last updated, Version 10) |
Name | ParB_Noc |
Scope(s) |
Bacteria Bacillales |
Template(s) | P37524 (NOC_BACSU); [ Recover all ] |
Triggered by |
HAMAP; MF_02015 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | NOC |
Protein name | RecName: Full=Nucleoid occlusion protein; Short=Noc; |
Gene name | Name=noc; |
Comments
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FUNCTION | Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage. |
SUBCELLULAR LOCATION | Cytoplasm, nucleoid. |
SIMILARITY | Belongs to the ParB family. |
Keywords
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Gene Ontology
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GO:0005737; Cellular component:cytoplasm |
GO:0003677; Molecular function:DNA binding |
GO:0051301; Biological process:cell division |
GO:0090529; Biological process:cell septum assembly |
Cross-references
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Features
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From: NOC_BACSU (P37524) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
DNA_BIND | 148 | 167 | /note="H-T-H motif" |
Additional information
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Size range | 281-298 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |