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HAMAP rule MF_02017

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General rule information [?]

Accession MF_02017
Dates 18-DEC-2008 (Created)
20-NOV-2019 (Last updated, Version 11)
Name RodZ
Bacteria; Enterobacterales
Template P27434 (RODZ_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Cytoskeleton protein RodZ;
Gene name

Comments [?]

Function Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
Subcellular location Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Domain The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.
Similarity Belongs to the RodZ family.

Keywords [?]

Gene Ontology [?]

GO:0008360; Biological process: regulation of cell shape.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF01381; HTH_3; 1;

Computed features [?]

General Transmembrane; -; 1;

Features [?]

From: RODZ_ECOLI (P27434)
Key     From     To       Description   Tag   Condition   FTGroup
TOPO_DOM     Nter     111       Cytoplasmic        
TRANSMEM     112     132       Helical; Signal-anchor for type II membrane protein        
TOPO_DOM     133     Cter       Periplasmic        
DOMAIN     19     71       HTH cro/C1-type        
DNA_BIND     30     49       H-T-H motif        

Additional information [?]

Size range 321-368 amino acids
Related rules None
Fusion None