HAMAP rule MF_02017

General rule information [?]

Accession	MF_02017
Dates	18-DEC-2008 (Created) 20-NOV-2019 (Last updated, Version 11)

Name

RodZ

Scope

Bacteria; Enterobacterales

Template

P27434 (RODZ_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

RODZ

Protein name

RecName:

Full=Cytoskeleton protein RodZ;

Gene name

rodZ

Comments [?]

Function	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
Subcellular location	Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Domain	The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.
Similarity	Belongs to the RodZ family.

Keywords [?]

Gene Ontology [?]

GO:0008360; Biological process: regulation of cell shape.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

PROSITE	PS50943; HTH_CROC1; 1;
Pfam	PF01381; HTH_3; 1;

Computed features [?]

General

Transmembrane; -; 1;

Features [?]

From: RODZ_ECOLI (P27434)

Key From To Description Tag Condition FTGroup

TOPO_DOM Nter 111 Cytoplasmic

TRANSMEM 112 132 Helical; Signal-anchor for type II membrane protein

TOPO_DOM 133 Cter Periplasmic

DOMAIN 19 71 HTH cro/C1-type

DNA_BIND 30 49 H-T-H motif

Additional information [?]