HAMAP rule MF_02017
General rule information
[?]
Accession | MF_02017 |
Dates | 18-DEC-2008 (Created) 20-NOV-2019 (Last updated, Version 11) |
Name | RodZ |
Scope | Bacteria; Enterobacterales |
Template | P27434 (RODZ_ECOLI) |
Triggered by |
Propagated annotation
[?]
Identifier, protein and gene names
[?]
Identifier |
|
Protein name |
|
Gene name |
|
Comments
[?]
Function | Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. |
Subcellular location | Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell. |
Domain | The helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm. |
Similarity | Belongs to the RodZ family. |
Keywords
[?]
Cell inner membrane
Cell membrane
Cell shape
Membrane
Signal-anchor
Transmembrane
Transmembrane helix
Cell membrane
Cell shape
Membrane
Signal-anchor
Transmembrane
Transmembrane helix
Gene Ontology
[?]
GO:0008360; Biological process: regulation of cell shape.
GO:0005886; Cellular component: plasma membrane.
GO:0005886; Cellular component: plasma membrane.
Cross-references
[?]
Computed features
[?]
General | Transmembrane; -; 1; |
Features
[?]
From: RODZ_ECOLI (P27434) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
TOPO_DOM | Nter | 111 | Cytoplasmic | |||||||||
TRANSMEM | 112 | 132 | Helical; Signal-anchor for type II membrane protein | |||||||||
TOPO_DOM | 133 | Cter | Periplasmic | |||||||||
DOMAIN | 19 | 71 | HTH cro/C1-type | |||||||||
DNA_BIND | 30 | 49 | H-T-H motif |
Additional information
[?]
Size range | 321-368 amino acids |
Related rules | None |
Fusion | None |