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HAMAP rule MF_02017

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General rule information [?]

Accession MF_02017
Dates 18-DEC-2008 (Created)
20-NOV-2019 (Last updated, Version 11)
Name RodZ
Scope(s) Bacteria
Enterobacterales
Template(s) P27434 (RODZ_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02017 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier RODZ
Protein name RecName: Full=Cytoskeleton protein RodZ;
Gene name Name=rodZ;

Comments [?]

FUNCTIONCytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
SUBCELLULAR LOCATIONCell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
DOMAINThe helix-turn-helix (HTH) motif in the cytoplasmic domain of the N-terminus is involved in the formation of spirals to maintain the rigid rod shape. As this protein is anchored in the cytoplasmic membrane, the HTH motif may contribute to protein-protein interactions to form the RodZ helix, which is localized beneath the cytoplasmic membrane. The C-terminal domain may be critical for determination of the rod shape by probably interacting with enzymes required for synthesis of the peptidoglycan layer, including PBPs in the periplasm.
SIMILARITYBelongs to the RodZ family.

Keywords [?]


Gene Ontology [?]

GO:0008360; Biological process:regulation of cell shape
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

PROSITE PS50943; HTH_CROC1; 1;
Pfam PF01381; HTH_3; 1;
General Transmembrane; -; 1;

Features [?]

From: RODZ_ECOLI (P27434)
Key From To Description Tag Condition FTGroup
TOPO_DOM Nter 111 /note="Cytoplasmic"
TRANSMEM 112 132 /note="Helical; Signal-anchor for type II membrane protein"
TOPO_DOM 133 Cter /note="Periplasmic"
DOMAIN 19 71 /note="HTH cro/C1-type"
DNA_BIND 30 49 /note="H-T-H motif"

Additional information [?]

Size range 321-368 amino acids
Related rules None
Fusion Nter: None Cter: None



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