HAMAP rule MF_02024

General rule information [?]

Accession	MF_02024
Dates	21-APR-2015 (Created) 29-SEP-2022 (Last updated, Version 4)

Name

WzxE

Scope

Bacteria; Enterobacterales

Template

P0AAA7 (WZXE_ECOLI)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

WZXE

Protein name

RecName:

Full=Lipid III flippase;

Gene name

wzxE

Comments [?]

Function	Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
Pathway	Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
Subunit	Probably part of a complex composed of WzxE, WzyE and WzzE.
Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Similarity	Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.

Keywords [?]

Gene Ontology [?]

GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam	PF01943; Polysacc_synt; 1;

Computed features [?]

General

Transmembrane; -; 12; trigger=yes;

Additional information [?]