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HAMAP rule MF_02024

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General rule information [?]

Accession MF_02024
Dates 21-APR-2015 (Created)
29-SEP-2022 (Last updated, Version 4)
Name WzxE
Scope(s) Bacteria
Template(s) P0AAA7 (WZXE_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02024 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier WZXE
Protein name RecName: Full=Lipid III flippase;
Gene name Name=wzxE;

Comments [?]

FUNCTIONMediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
PATHWAYBacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
SUBUNITProbably part of a complex composed of WzxE, WzyE and WzzE.
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
SIMILARITYBelongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.

Keywords [?]

Gene Ontology [?]

GO:0009246; Biological process:enterobacterial common antigen biosynthetic process
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF01943; Polysacc_synt; 1;
General Transmembrane; -; 12;

Features [?]

Additional information [?]

Size range 400-430 amino acids
Related rules None
Fusion Nter: None Cter: None

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