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Annotation rule MF_02024
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General rule information [?]

Accession MF_02024
Dates 21-APR-2015 (Created)
20-NOV-2019 (Last updated, Version 3)
Name WzxE
Scope
Bacteria; Enterobacterales
Template P0AAA7 (WZXE_ECOLI)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
WZXE
Protein name
RecName: Full=Lipid III flippase;
Gene name
wzxE

Comments [?]

Function Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
Pathway Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
Subunit Probably part of a complex composed of WzxE, WzyE and WzzE.
Subcellular location Cell inner membrane; Multi-pass membrane protein.
Similarity Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.

Keywords [?]

Cell inner membrane
Cell membrane
Membrane
Transmembrane
Transmembrane helix
Transport

Gene Ontology [?]

GO:0009246; Biological process: enterobacterial common antigen biosynthetic process.
GO:0005887; Cellular component: integral component of plasma membrane.

Cross-references [?]

Pfam PF01943; Polysacc_synt; 1;

Computed features [?]

General Transmembrane; -; 12; trigger=yes;

Additional information [?]

Size range 400-430 amino acids
Related rules None
Fusion None


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