HAMAP rule MF_02024

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_02024
Accession	MF_02024
Dates	21-APR-2015 (Created) 29-SEP-2022 (Last updated, Version 5)
Name	WzxE
Scope(s)	Bacteria Enterobacterales
Template(s)	P0AAA7; [ Recover all ]
Triggered by	HAMAP; MF_02024 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	WZXE
Protein name	RecName: Full=Lipid III flippase;
Gene name	Name=wzxE;

Comments [?]

FUNCTION	Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA).
PATHWAY	Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
SUBUNIT	Probably part of a complex composed of WzxE, WzyE and WzzE.
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
SIMILARITY	Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family.

Keywords [?]

Gene Ontology [?]

GO:0009246; Biological process:enterobacterial common antigen biosynthetic process

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam	PF01943; Polysacc_synt; 1;
General	Transmembrane; -; 12;

Features [?]

Additional information [?]