HAMAP rule MF_02024
General rule information
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Accession | MF_02024 |
Dates | 21-APR-2015 (Created)
29-SEP-2022 (Last updated, Version 4) |
Name | WzxE |
Scope(s) |
Bacteria Enterobacterales |
Template(s) | P0AAA7 (WZXE_ECOLI); [ Recover all ] |
Triggered by |
HAMAP; MF_02024 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | WZXE |
Protein name | RecName: Full=Lipid III flippase; |
Gene name | Name=wzxE; |
Comments
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FUNCTION | Mediates the transbilayer movement of Und-PP-GlcNAc-ManNAcA- Fuc4NAc (lipid III) from the inner to the outer leaflet of the cytoplasmic membrane during the assembly of enterobacterial common antigen (ECA). |
PATHWAY | Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis. |
SUBUNIT | Probably part of a complex composed of WzxE, WzyE and WzzE. |
SUBCELLULAR LOCATION | Cell inner membrane; Multi-pass membrane protein. |
SIMILARITY | Belongs to the polysaccharide transport (PST) (TC 2.A.66.2) family. |
Keywords
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Gene Ontology
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GO:0009246; Biological process:enterobacterial common antigen biosynthetic process |
GO:0005886; Cellular component:plasma membrane |
Cross-references
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Pfam | PF01943; Polysacc_synt; 1; |
General | Transmembrane; -; 12; |
Features
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Additional information
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Size range | 400-430 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |