HAMAP rule MF_02031

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_02031
Accession	MF_02031
Dates	26-MAY-2015 (Created) 01-JUN-2023 (Last updated, Version 7)
Name	Galactar_dehydrat
Scope(s)	Bacteria Gammaproteobacteria
Template(s)	P39829; [ Recover all ]
Triggered by	HAMAP; MF_02031 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	GARD
Protein name	RecName: Full=Galactarate dehydratase (L-threo-forming); Short=GalcD; EC=4.2.1.42;
Gene name	Name=garD;

Comments [?]

FUNCTION	Catalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate (5-KDG).
CATALYTIC ACTIVITY	Reaction=galactarate = 5-dehydro-4-deoxy-D-glucarate + H2O; Xref=Rhea:RHEA:16005, ChEBI:CHEBI:15377, ChEBI:CHEBI:16537, ChEBI:CHEBI:42819; EC=4.2.1.42; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16006;
COFACTOR	Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
PATHWAY	Carbohydrate acid metabolism; galactarate degradation; D- glycerate from galactarate: step 1/3.
SIMILARITY	Belongs to the UxaA family.

Keywords [?]

Gene Ontology [?]

GO:0008867; Molecular function:galactarate dehydratase activity

GO:0046392; Biological process:galactarate catabolic process

Cross-references [?]

Features [?]

Additional information [?]