HAMAP logo

HAMAP rule MF_02031

Send feedback

General rule information [?]

Accession MF_02031
Dates 26-MAY-2015 (Created)
1-JUN-2023 (Last updated, Version 6)
Name Galactar_dehydrat
Scope(s) Bacteria
Template(s) P39829 (GARD_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02031 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GARD
Protein name RecName: Full=Galactarate dehydratase (L-threo-forming);
Gene name Name=garD;

Comments [?]

FUNCTIONCatalyzes the dehydration of galactarate to form 5-dehydro-4- deoxy-D-glucarate (5-KDG).
CATALYTIC ACTIVITY Reaction=galactarate = 5-dehydro-4-deoxy-D-glucarate + H2O; Xref=Rhea:RHEA:16005, ChEBI:CHEBI:15377, ChEBI:CHEBI:16537, ChEBI:CHEBI:42819; EC=; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16006;
COFACTOR Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
PATHWAYCarbohydrate acid metabolism; galactarate degradation; D- glycerate from galactarate: step 1/3.
SIMILARITYBelongs to the UxaA family.

Keywords [?]

Gene Ontology [?]

GO:0008867; Molecular function:galactarate dehydratase activity
GO:0046392; Biological process:galactarate catabolic process

Cross-references [?]

Pfam PF04295; GD_AH_C; 1;
Pfam PF08666; SAF; 1;
NCBIfam TIGR03248; galactar-dH20; 1;

Features [?]

Additional information [?]

Size range 500-530 amino acids
Related rules None
Fusion Nter: None Cter: None

View rule in raw text format (no links)