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HAMAP rule MF_02036

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General rule information [?]

Accession MF_02036
Dates 1-JUL-2015 (Created)
1-JUN-2023 (Last updated, Version 7)
Name EgtC
Scope(s) Bacteria
Template(s) A0R5M9 (EGTC_MYCS2); [ Recover all ]
Triggered by HAMAP; MF_02036 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier EGTC
Protein name RecName: Full=Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase;
AltName: Full=Gamma-glutamyl hercynylcysteine S-oxide hydrolase;
Gene name Name=egtC;

Comments [?]

FUNCTIONCatalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.
CATALYTIC ACTIVITY Reaction=gamma-L-glutamyl-hercynylcysteine S-oxide + H2O = L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide; Xref=Rhea:RHEA:42684, ChEBI:CHEBI:15377, ChEBI:CHEBI:29985, ChEBI:CHEBI:82703, ChEBI:CHEBI:82706; EC=;
PATHWAYAmino-acid biosynthesis; ergothioneine biosynthesis.

Keywords [?]

Gene Ontology [?]

GO:0016811; Molecular function:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0052699; Biological process:ergothioneine biosynthetic process

Cross-references [?]

NCBIfam TIGR03442; TIGR03442; 1;

Features [?]

Additional information [?]

Size range 223-301 amino acids
Related rules None
Fusion Nter: None Cter: None

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