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HAMAP rule MF_02036

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General rule information [?]

Accession MF_02036
Dates 1-JUL-2015 (Created)
1-JUN-2023 (Last updated, Version 7)
Name EgtC
Bacteria; Actinomycetota
Template A0R5M9 (EGTC_MYCS2)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase;
AltName: Full=Gamma-glutamyl hercynylcysteine S-oxide hydrolase;
Gene name

Comments [?]

Function Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.
Catalytic activity RHEA:42684: gamma-L-glutamyl-hercynylcysteine S-oxide + H2O = L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide
Pathway Amino-acid biosynthesis; ergothioneine biosynthesis.

Keywords [?]

Gene Ontology [?]

GO:0016811; Molecular function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides.
GO:0052699; Biological process: ergothioneine biosynthetic process.

Cross-references [?]

PROSITE PS51278; GATASE_TYPE_2; 1; trigger=PRU00609;
NCBIfam TIGR03442; TIGR03442; 1;

Additional information [?]

Size range 223-301 amino acids
Related rules None
Fusion None