HAMAP rule MF_02036
General rule information
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Accession | MF_02036 |
Dates | 1-JUL-2015 (Created)
1-JUN-2023 (Last updated, Version 7) |
Name | EgtC |
Scope(s) |
Bacteria Actinomycetota |
Template(s) | A0R5M9 (EGTC_MYCS2); [ Recover all ] |
Triggered by |
HAMAP; MF_02036 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | EGTC |
Protein name | RecName: Full=Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase; EC=3.5.1.118; AltName: Full=Gamma-glutamyl hercynylcysteine S-oxide hydrolase; |
Gene name | Name=egtC; |
Comments
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FUNCTION | Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. |
CATALYTIC ACTIVITY | Reaction=gamma-L-glutamyl-hercynylcysteine S-oxide + H2O = L-glutamate + S-(hercyn-2-yl)-L-cysteine S-oxide; Xref=Rhea:RHEA:42684, ChEBI:CHEBI:15377, ChEBI:CHEBI:29985, ChEBI:CHEBI:82703, ChEBI:CHEBI:82706; EC=3.5.1.118; |
PATHWAY | Amino-acid biosynthesis; ergothioneine biosynthesis. |
Keywords
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Gene Ontology
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GO:0016811; Molecular function:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides |
GO:0052699; Biological process:ergothioneine biosynthetic process |
Cross-references
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Features
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Additional information
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Size range | 223-301 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |