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HAMAP rule MF_02038

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General rule information [?]

Accession MF_02038
Dates 1-JUL-2015 (Created)
1-JUN-2023 (Last updated, Version 5)
Name EgtE
Scope(s) Bacteria
Template(s) A0R5M7 (EGTE_MYCS2); [ Recover all ]
Triggered by HAMAP; MF_02038 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier EGTE
Protein name RecName: Full=Probable hercynylcysteine sulfoxide lyase;
Gene name Name=egtE;

Comments [?]

FUNCTIONProbably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine.
CATALYTIC ACTIVITY Reaction=AH2 + H(+) + S-(hercyn-2-yl)-L-cysteine S-oxide = A + ergothioneine + NH4(+) + pyruvate; Xref=Rhea:RHEA:42688, ChEBI:CHEBI:13193, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378, ChEBI:CHEBI:17499, ChEBI:CHEBI:28938, ChEBI:CHEBI:82706, ChEBI:CHEBI:134344;
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
PATHWAYAmino-acid biosynthesis; ergothioneine biosynthesis.
SIMILARITYBelongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.

Keywords [?]

Gene Ontology [?]

GO:0016846; Molecular function:carbon-sulfur lyase activity
GO:0052699; Biological process:ergothioneine biosynthetic process

Cross-references [?]

Pfam PF00266; Aminotran_5; 1;
NCBIfam TIGR04343; egtE_PLP_lyase; 1;

Features [?]

From: EGTE_MYCS2 (A0R5M7)
Key From To Description Tag Condition FTGroup
MOD_RES 203 203 /note="N6-(pyridoxal phosphate)lysine" K

Additional information [?]

Size range 359-425 amino acids
Related rules None
Fusion Nter: None Cter: None

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