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Annotation rule MF_02038
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General rule information [?]

Accession MF_02038
Dates 1-JUL-2015 (Created)
20-NOV-2019 (Last updated, Version 3)
Name EgtE
Scope
Bacteria; Actinobacteria
Template A0R5M7 (EGTE_MYCS2)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
EGTE
Protein name
RecName: Full=Probable hercynylcysteine sulfoxide lyase;
EC 4.4.-.-;
Gene name
egtE

Comments [?]

Function Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine.
Catalytic activity RHEA:42688: AH2 + H(+) + S-(hercyn-2-yl)-L-cysteine S-oxide = A + ergothioneine + NH4(+) + pyruvate
Cofactor pyridoxal 5'-phosphate
Pathway Amino-acid biosynthesis; ergothioneine biosynthesis.
Similarity Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. EgtE subfamily.

Keywords [?]

Lyase
Pyridoxal phosphate

Gene Ontology [?]

GO:0016846; Molecular function: carbon-sulfur lyase activity.
GO:0052699; Biological process: ergothioneine biosynthetic process.

Cross-references [?]

Pfam PF00266; Aminotran_5; 1;
TIGRFAMs TIGR04343; egtE_PLP_lyase; 1;

Features [?]

From: EGTE_MYCS2 (A0R5M7)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     203     203       N6-(pyridoxal phosphate)lysine     K  

Additional information [?]

Size range 359-425 amino acids
Related rules None
Fusion None


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