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HAMAP rule MF_02051

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General rule information [?]

Accession MF_02051
Dates 7-JAN-2016 (Created)
5-MAY-2020 (Last updated, Version 5)
Name LsrG
Bacteria; Enterobacterales
Template P64461 (LSRG_ECOLI)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase;
AltName: Full=Autoinducer 2-degrading protein LsrG;
Short=AI-2-degrading protein LsrG;
AltName: Full=Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase;
AltName: Full=Phospho-AI-2 isomerase;
Gene name

Comments [?]

Function Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
Catalytic activity RHEA:44360: (2S)-2-hydroxy-3,4-dioxopentyl phosphate = 3-hydroxy-2,4-dioxopentyl phosphate
Subunit Homodimer.
Subcellular location Cytoplasm.
Similarity Belongs to the LsrG family.

Keywords [?]

Gene Ontology [?]

GO:0016861; Molecular function: intramolecular oxidoreductase activity, interconverting aldoses and ketoses.
GO:0005737; Cellular component: cytoplasm.

Cross-references [?]

PROSITE PS51725; ABM; 1; trigger=PRU01062;
Pfam PF03992; ABM; 1;

Additional information [?]

Size range 95-111 amino acids
Related rules None
Fusion None