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HAMAP rule MF_02051

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General rule information [?]

Accession MF_02051
Dates 7-JAN-2016 (Created)
5-MAY-2020 (Last updated, Version 5)
Name LsrG
Scope(s) Bacteria
Template(s) P64461 (LSRG_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02051 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier LSRG
Protein name RecName: Full=(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase;
AltName: Full=Autoinducer 2-degrading protein LsrG;
                 Short=AI-2-degrading protein LsrG;
AltName: Full=Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase;
AltName: Full=Phospho-AI-2 isomerase;
Gene name Name=lsrG;

Comments [?]

FUNCTIONInvolved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the conversion of (4S)-4-hydroxy-5- phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5- phosphonooxypentane-2,4-dione (P-HPD).
CATALYTIC ACTIVITY Reaction=(2S)-2-hydroxy-3,4-dioxopentyl phosphate = 3-hydroxy-2,4- dioxopentyl phosphate; Xref=Rhea:RHEA:44360, ChEBI:CHEBI:71677, ChEBI:CHEBI:84359; EC=;
SIMILARITYBelongs to the LsrG family.

Keywords [?]

Gene Ontology [?]

GO:0016861; Molecular function:intramolecular oxidoreductase activity, interconverting aldoses and ketoses
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

PROSITE PS51725; ABM; 1;
Pfam PF03992; ABM; 1;

Features [?]

Additional information [?]

Size range 95-111 amino acids
Related rules None
Fusion Nter: None Cter: None

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