HAMAP rule MF_02064
General rule information
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| Accession | MF_02064 |
| Dates | 25-APR-2016 (Created) 1-JUN-2023 (Last updated, Version 10) |
| Name | Sigma70_SigI |
| Scope | Bacteria; Bacillota |
| Template | O31654 (SIGI_BACSU) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. |
| Activity regulation | Negatively regulated by the anti-sigma-I factor RsgI. |
| Subunit | Interacts with RsgI. |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the sigma-70 factor family. SigI subfamily. |
Keywords
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Gene Ontology
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GO:0003677; Molecular function: DNA binding.
GO:0016987; Molecular function: sigma factor activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0006352; Biological process: DNA-templated transcription initiation.
GO:0005737; Cellular component: cytoplasm.
GO:0016987; Molecular function: sigma factor activity.
GO:0010468; Biological process: regulation of gene expression.
GO:0006352; Biological process: DNA-templated transcription initiation.
GO:0005737; Cellular component: cytoplasm.
Cross-references
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| Pfam | PF04542; Sigma70_r2; 1; |
| NCBIfam | TIGR02937; sigma70-ECF; 1; |
| TIGR02895; spore_sigI; 1; | |
| PIRSF | PIRSF038953; SigI; 1; |
Features
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| From: SIGI_BACSU (O31654) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | 206 | 225 | H-T-H motif | |||||||||
| MOTIF | 61 | 74 | Polymerase core binding | |||||||||
Additional information
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| Size range | 209-290 amino acids |
| Related rules | None |
| Fusion | None |