HAMAP rule MF_02064
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_02064 |
| Accession | MF_02064 |
| Dates | 25-APR-2016 (Created)
1-JUN-2023 (Last updated, Version 10) |
| Name | Sigma70_SigI |
| Scope(s) |
Bacteria Bacillota |
| Template(s) | O31654 (SIGI_BACSU); [ Recover all ] |
| Triggered by |
HAMAP; MF_02064 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | SIGI |
| Protein name | RecName: Full=RNA polymerase sigma factor SigI; |
| Gene name | Name=sigI; |
Comments
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| FUNCTION | Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. |
| ACTIVITY REGULATION | Negatively regulated by the anti-sigma-I factor RsgI. |
| SUBUNIT | Interacts with RsgI. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the sigma-70 factor family. SigI subfamily. |
Keywords
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Gene Ontology
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| GO:0003677; Molecular function:DNA binding |
| GO:0016987; Molecular function:sigma factor activity |
| GO:0010468; Biological process:regulation of gene expression |
| GO:0006352; Biological process:DNA-templated transcription initiation |
| GO:0005737; Cellular component:cytoplasm |
Cross-references
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| Pfam | PF04542; Sigma70_r2; 1; |
| NCBIfam | TIGR02937; sigma70-ECF; 1; |
| NCBIfam | TIGR02895; spore_sigI; 1; |
| PIRSF | PIRSF038953; SigI; 1; |
Features
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| From: SIGI_BACSU (O31654) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| DNA_BIND | 206 | 225 | /note="H-T-H motif" | |||||||||
| MOTIF | 61 | 74 | /note="Polymerase core binding" | |||||||||
Additional information
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| Size range | 209-290 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |