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HAMAP rule MF_02065

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General rule information [?]

Accession MF_02065
Dates 19-MAY-2016 (Created)
1-JUN-2023 (Last updated, Version 6)
Name MltG
Templates P28306 (MLTG_ECOLI); A0A0H2ZLQ1 (MLTG_STRP2): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Endolytic murein transglycosylase;
EC 4.2.2.-;
AltName: Full=Peptidoglycan polymerization terminase;
Gene name

Comments [?]

Function Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
case ((defined <Property:Membrane> and <Property:Membrane=2>) or <OC:Pseudomonadota>) and <Feature:Transmembrane==1>
Subcellular location Cell inner membrane; Single-pass membrane protein.
else case <Feature:Transmembrane==1>
Subcellular location Cell membrane; Single-pass membrane protein.
end case
Similarity Belongs to the transglycosylase MltG family.

Keywords [?]

case (defined <Property:Membrane> and <Property:Membrane=2>) or <OC:Pseudomonadota>
end case

Gene Ontology [?]

GO:0008932; Molecular function: lytic endotransglycosylase activity.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF02618; YceG; 1;
NCBIfam TIGR00247; TIGR00247; 1;

Computed features [?]

General Transmembrane; -; 1; trigger=yes;

Features [?]

From: MLTG_ECOLI (P28306)
Key     From     To       Description   Tag   Condition   FTGroup
SITE     218     218       Important for catalytic activity     E  

Additional information [?]

Size range 250-680 amino acids
Related rules None
Fusion None
Comments Rod-shaped bacteria contain a short N-terminal cytoplasmic domain (<20 aa) and ovoid bacteria contain a long N-terminal cytoplasmic domain (150-200 aa). (PubMed:26933838)