HAMAP rule MF_02070
General rule information
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Accession | MF_02070 |
Dates | 19-JUL-2016 (Created)
1-JUN-2023 (Last updated, Version 7) |
Name | TagA_TarA |
Scope(s) |
Bacteria Bacillota |
Template(s) | P27620 (TAGA_BACSU); Q8RKI7 (TARA_BACSH); [ Recover all ] |
Triggered by |
HAMAP; MF_02070 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | TAGA |
Protein name | RecName: Full=N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; EC=2.4.1.187; AltName: Full=N-acetylmannosaminyltransferase; AltName: Full=UDP-N-acetylmannosamine transferase; AltName: Full=UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase; |
Comments
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FUNCTION | Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. |
CATALYTIC ACTIVITY | Reaction=N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-mannosamine = H(+) + N-acetyl- beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di- trans,octa-cis-undecaprenyl diphosphate + UDP; Xref=Rhea:RHEA:16053, ChEBI:CHEBI:15378, ChEBI:CHEBI:58223, ChEBI:CHEBI:62959, ChEBI:CHEBI:68623, ChEBI:CHEBI:132210; EC=2.4.1.187; |
PATHWAY | Cell wall biogenesis; teichoic acid biosynthesis. |
SIMILARITY | Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily. |
Keywords
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Gene Ontology
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GO:0047244; Molecular function:N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity |
GO:0019350; Biological process:teichoic acid biosynthetic process |
Cross-references
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Features
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Additional information
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Size range | 220-282 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |