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HAMAP rule MF_02070

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General rule information [?]

Accession MF_02070
Dates 19-JUL-2016 (Created)
1-JUN-2023 (Last updated, Version 7)
Name TagA_TarA
Scope(s) Bacteria
Template(s) P27620 (TAGA_BACSU); Q8RKI7 (TARA_BACSH); [ Recover all ]
Triggered by HAMAP; MF_02070 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier TAGA
Protein name RecName: Full=N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase;
AltName: Full=N-acetylmannosaminyltransferase;
AltName: Full=UDP-N-acetylmannosamine transferase;
AltName: Full=UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase;

Comments [?]

FUNCTIONCatalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
CATALYTIC ACTIVITY Reaction=N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-mannosamine = H(+) + N-acetyl- beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di- trans,octa-cis-undecaprenyl diphosphate + UDP; Xref=Rhea:RHEA:16053, ChEBI:CHEBI:15378, ChEBI:CHEBI:58223, ChEBI:CHEBI:62959, ChEBI:CHEBI:68623, ChEBI:CHEBI:132210; EC=;
PATHWAYCell wall biogenesis; teichoic acid biosynthesis.
SIMILARITYBelongs to the glycosyltransferase 26 family. TagA/TarA subfamily.

Keywords [?]

Gene Ontology [?]

GO:0047244; Molecular function:N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity
GO:0019350; Biological process:teichoic acid biosynthetic process

Cross-references [?]

Pfam PF03808; Glyco_tran_WecB; 1;
NCBIfam TIGR00696; wecG_tagA_cpsF; 1;

Features [?]

Additional information [?]

Size range 220-282 amino acids
Related rules None
Fusion Nter: None Cter: None

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