HAMAP rule MF_02070

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_02070
Accession	MF_02070
Dates	19-JUL-2016 (Created) 03-SEP-2024 (Last updated, Version 9)
Name	TagA_TarA
Scope(s)	Bacteria Bacillota
Template(s)	P27620; Q8RKI7; [ Recover all ]
Triggered by	HAMAP; MF_02070 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	TAGA
Protein name	RecName: Full=N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; EC=2.4.1.187; AltName: Full=N-acetylmannosaminyltransferase; AltName: Full=UDP-N-acetylmannosamine transferase; AltName: Full=UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase;

Comments [?]

FUNCTION	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
CATALYTIC ACTIVITY	Reaction=UDP-N-acetyl-alpha-D-mannosamine + N-acetyl-alpha-D- glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate = N-acetyl- beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di- trans,octa-cis-undecaprenyl diphosphate + UDP + H(+); Xref=Rhea:RHEA:16053, ChEBI:CHEBI:15378, ChEBI:CHEBI:58223, ChEBI:CHEBI:62959, ChEBI:CHEBI:68623, ChEBI:CHEBI:132210; EC=2.4.1.187;
PATHWAY	Cell wall biogenesis; teichoic acid biosynthesis.
SIMILARITY	Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.

Keywords [?]

Gene Ontology [?]

GO:0047244; Molecular function:N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity

GO:0019350; Biological process:teichoic acid biosynthetic process

Cross-references [?]

Pfam	PF03808; Glyco_tran_WecB; 1;
NCBIfam	TIGR00696; wecG_tagA_cpsF; 1;

Features [?]

Additional information [?]