HAMAP rule MF_02070

General rule information [?]

Accession	MF_02070
Dates	19-JUL-2016 (Created) 1-JUN-2023 (Last updated, Version 7)

Name

TagA_TarA

Scope

Bacteria; Bacillota

Templates

P27620 (TAGA_BACSU); Q8RKI7 (TARA_BACSH): [Recover all]

Triggered by

HAMAP; MF_02070 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

TAGA

Protein name

RecName:		Full=N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase;
		EC 2.4.1.187;
AltName:		Full=N-acetylmannosaminyltransferase;
AltName:		Full=UDP-N-acetylmannosamine transferase;
AltName:		Full=UDP-N-acetylmannosamine:N-acetylglucosaminyl pyrophosphorylundecaprenol N-acetylmannosaminyltransferase;

Comments [?]

Function	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
Catalytic activity	RHEA:16053: N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UDP-N-acetyl-alpha-D-mannosamine = H(+) + N-acetyl-beta-D-mannosaminyl-(1->4)-N-acetyl-alpha-D-glucosaminyl di-trans,octa-cis-undecaprenyl diphosphate + UDP EC 2.4.1.187
Pathway	Cell wall biogenesis; teichoic acid biosynthesis.
Similarity	Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.

Keywords [?]

Cell wall biogenesis/degradation
Glycosyltransferase
Teichoic acid biosynthesis
Transferase

Gene Ontology [?]

GO:0047244; Molecular function: N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity.
GO:0019350; Biological process: teichoic acid biosynthetic process.

Cross-references [?]

Pfam	PF03808; Glyco_tran_WecB; 1;
NCBIfam	TIGR00696; wecG_tagA_cpsF; 1;

Additional information [?]

Size range	220-282 amino acids
Related rules	None
Fusion	None

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