HAMAP rule MF_02073

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_02073
Accession	MF_02073
Dates	24-AUG-2016 (Created) 03-SEP-2024 (Last updated, Version 8)
Name	Putrescine_transp
Scope(s)	Bacteria
Template(s)	P0AAF1; [ Recover all ]
Triggered by	HAMAP; MF_02073 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	POTE
case <OC:Gammaproteobacteria>
Protein name	RecName: Full=Putrescine transporter PotE; AltName: Full=Putrescine-proton symporter / putrescine-ornithine antiporter;
Gene name	Name=potE;
else
Protein name	RecName: Full=Putrescine transporter;
end case

Comments [?]

case <OC:Gammaproteobacteria>
FUNCTION	Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity.
CATALYTIC ACTIVITY	Reaction=putrescine(in) + H(+)(in) = putrescine(out) + H(+)(out); Xref=Rhea:RHEA:28891, ChEBI:CHEBI:15378, ChEBI:CHEBI:326268; PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:28893;
CATALYTIC ACTIVITY	Reaction=putrescine(in) + L-ornithine(out) = putrescine(out) + L- ornithine(in); Xref=Rhea:RHEA:28827, ChEBI:CHEBI:46911, ChEBI:CHEBI:326268; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:28828;
end case
case <OC:Pseudomonadota>
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
else
SUBCELLULAR LOCATION	Cell membrane; Multi-pass membrane protein.
end case
SIMILARITY	Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.

Keywords [?]

case <OC:Pseudomonadota>
Cell inner membrane
end case
Cell membrane
Membrane
Transmembrane
Transmembrane helix
Transport
case <OC:Gammaproteobacteria>
Amino-acid transport
Antiport
Symport
end case

Gene Ontology [?]

GO:0015489; Molecular function:putrescine transmembrane transporter activity

GO:0015847; Biological process:putrescine transport

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]