HAMAP rule MF_02078

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_02078
Accession	MF_02078
Dates	18-NOV-2016 (Created) 01-JUN-2023 (Last updated, Version 6)
Name	MurJ_MviN
Scope(s)	Bacteria
Template(s)	P0AF16; B4E9G3; [ Recover all ]
Triggered by	HAMAP; MF_02078 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MURJ
Protein name	RecName: Full=Probable lipid II flippase MurJ;
Gene name	Name=murJ;

Comments [?]

FUNCTION	Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
PATHWAY	Cell wall biogenesis; peptidoglycan biosynthesis.
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
SUBCELLULAR LOCATION	Cell inner membrane; Multi-pass membrane protein.
else
SUBCELLULAR LOCATION	Cell membrane; Multi-pass membrane protein.
end case
SIMILARITY	Belongs to the MurJ/MviN family.

Keywords [?]

case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
Cell inner membrane
end case
Cell membrane
Cell shape
Cell wall biogenesis/degradation
Membrane
Peptidoglycan synthesis
Transmembrane
Transmembrane helix
Transport

Gene Ontology [?]

GO:0015648; Molecular function:lipid-linked peptidoglycan transporter activity

GO:0015836; Biological process:lipid-linked peptidoglycan transport

GO:0009252; Biological process:peptidoglycan biosynthetic process

GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Features [?]

Additional information [?]