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HAMAP rule MF_02078

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General rule information [?]

Accession MF_02078
Dates 18-NOV-2016 (Created)
26-JAN-2023 (Last updated, Version 4)
Name MurJ_MviN
Scope
Bacteria
Templates P0AF16 (MURJ_ECOLI); B4E9G3 (MURJ_BURCJ): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MURJ
Protein name
RecName: Full=Probable lipid II flippase MurJ;
Gene name
murJ

Comments [?]

Function Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
Pathway Cell wall biogenesis; peptidoglycan biosynthesis.
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
Subcellular location Cell inner membrane; Multi-pass membrane protein.
else
Subcellular location Cell membrane; Multi-pass membrane protein.
end case
Similarity Belongs to the MurJ/MviN family.

Keywords [?]

case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
Cell inner membrane
end case
Cell membrane
Cell shape
Cell wall biogenesis/degradation
Membrane
Peptidoglycan synthesis
Transmembrane
Transmembrane helix
Transport

Gene Ontology [?]

GO:0015648; Molecular function: lipid-linked peptidoglycan transporter activity.
GO:0015836; Biological process: lipid-linked peptidoglycan transport.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005886; Cellular component: plasma membrane.

Cross-references [?]

Pfam PF03023; MVIN; 1;
PRINTS PR01806; VIRFACTRMVIN; 1;
TIGRFAMs TIGR01695; murJ_mviN; 1;
PIRSF PIRSF002869; MviN; 1;

Computed features [?]

General Transmembrane; -; 12-15; trigger=yes;

Additional information [?]

Size range 440-600 amino acids
Related rules None
Fusion None


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