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HAMAP rule MF_02078

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General rule information [?]

Accession MF_02078
Dates 18-NOV-2016 (Created)
1-JUN-2023 (Last updated, Version 5)
Name MurJ_MviN
Scope(s) Bacteria
Template(s) P0AF16 (MURJ_ECOLI); B4E9G3 (MURJ_BURCJ); [ Recover all ]
Triggered by HAMAP; MF_02078 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MURJ
Protein name RecName: Full=Probable lipid II flippase MurJ;
Gene name Name=murJ;

Comments [?]

FUNCTIONInvolved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
PATHWAYCell wall biogenesis; peptidoglycan biosynthesis.
case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
SUBCELLULAR LOCATIONCell inner membrane; Multi-pass membrane protein.
SUBCELLULAR LOCATIONCell membrane; Multi-pass membrane protein.
end case
SIMILARITYBelongs to the MurJ/MviN family.

Keywords [?]

case <OC:Pseudomonadota> or (defined <Property:Membrane> and <Property:Membrane=2>)
Cell inner membrane
end case
Cell membrane
Cell shape
Cell wall biogenesis/degradation
Peptidoglycan synthesis
Transmembrane helix

Gene Ontology [?]

GO:0015648; Molecular function:lipid-linked peptidoglycan transporter activity
GO:0015836; Biological process:lipid-linked peptidoglycan transport
GO:0009252; Biological process:peptidoglycan biosynthetic process
GO:0005886; Cellular component:plasma membrane

Cross-references [?]

Pfam PF03023; MVIN; 1;
NCBIfam TIGR01695; murJ_mviN; 1;
PIRSF PIRSF002869; MviN; 1;
General Transmembrane; -; 12-15;

Features [?]

Additional information [?]

Size range 440-600 amino acids
Related rules None
Fusion Nter: None Cter: None

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