HAMAP rule MF_02085

General rule information [?]

Accession	MF_02085
Dates	6-JAN-2017 (Created) 17-FEB-2023 (Last updated, Version 6)

Name	CugP_cyano

Scope

Bacteria; Cyanobacteriota

Template

P74285 (CUGP_SYNY3)

Triggered by

HAMAP; MF_02085 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

CUGP

Protein name

RecName:		Full=UTP--glucose-1-phosphate uridylyltransferase;
		EC 2.7.7.9;
AltName:		Full=Cyanobacteriotal UDP-glucose pyrophosphorylase;
AltName:		Full=UDP-glucose pyrophosphorylase;
		Short=UDP-Glc PPase;

Gene name

cugP

Comments [?]

Function	Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate.
Catalytic activity	RHEA:19889: alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose EC 2.7.7.9
Cofactor	Mg(2+)
Similarity	Belongs to the CugP-type UDP-glucose pyrophosphorylase family.

Keywords [?]

Magnesium
Metal-binding
Nucleotidyltransferase
Transferase

Gene Ontology [?]

GO:0003983; Molecular function: UTP:glucose-1-phosphate uridylyltransferase activity.
GO:0002134; Molecular function: UTP binding.
GO:0000287; Molecular function: magnesium ion binding.
GO:0006011; Biological process: UDP-glucose metabolic process.

Cross-references [?]

Pfam	PF00483; NTP_transferase; 1;

Features [?]

From: CUGP_SYNY3 (P74285)

Key From To Description Tag Condition FTGroup

BINDING 118 118 /ligand="Mg(2+)" /ligand_id="ChEBI:CHEBI:18420 D

Additional information [?]

Size range	370-415 amino acids
Related rules	None
Fusion	None

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