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Annotation rule MF_02101
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General rule information [?]

Accession MF_02101
Dates 15-MAY-2009 (Created)
20-NOV-2019 (Last updated, Version 11)
Name DHNA_CoA_hydrolase
Scope
Bacteria; Cyanobacteria
Template Q55777 (DNCH_SYNY3)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
DNCH
Protein name
RecName: Full=1,4-dihydroxy-2-naphthoyl-CoA hydrolase;
Short=DHNA-CoA hydrolase;
EC 3.1.2.28;
AltName: Full=DHNA-CoA thioesterase;

Comments [?]

Function Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
Catalytic activity RHEA:26309: 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA + H(+)
EC 3.1.2.28
Pathway Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 7/7.
Cofactor biosynthesis; phylloquinone biosynthesis.
Similarity Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.

Keywords [?]

Hydrolase

Gene Ontology [?]

GO:0016790; Molecular function: thiolester hydrolase activity.
GO:0042372; Biological process: phylloquinone biosynthetic process.

Cross-references [?]

PROSITE PS01328; 4HBCOA_THIOESTERASE; 1;
Pfam PF03061; 4HBT; 1;

Features [?]

From: DNCH_SYNY3 (Q55777)
Key     From     To       Description   Tag   Condition   FTGroup
ACT_SITE     16     16             D  

Additional information [?]

Size range 131-160 amino acids
Related rules None
Fusion None


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