HAMAP rule MF_02108
General rule information
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Accession |
MF_02108 |
Dates |
5-OCT-2009 (Created) 29-JUN-2022 (Last updated, Version 14) |
Scope |
Bacteria; Enterobacterales |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=HTH-type transcriptional regulator MurR;
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AltName:
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Full=MurPQ operon repressor;
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Function |
Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator. |
Pathway |
Amino-sugar metabolism; N-acetylmuramate degradation [regulation]. |
Subunit |
Homotetramer. |
GO:0003700; Molecular function: DNA-binding transcription factor activity.
GO:0043470; Biological process: regulation of carbohydrate catabolic process.
GO:0045892; Biological process: negative regulation of DNA-templated transcription.
Additional information
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Size range |
266-287 amino acids |
Related rules |
None |
Fusion |
None |