HAMAP rule MF_02108

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_02108
Accession	MF_02108
Dates	05-OCT-2009 (Created) 29-JUN-2022 (Last updated, Version 15)
Name	HTH_type_MurR
Scope(s)	Bacteria Enterobacterales
Template(s)	P77245; [ Recover all ]
Triggered by	HAMAP; MF_02108 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	MURR
Protein name	RecName: Full=HTH-type transcriptional regulator MurR; AltName: Full=MurPQ operon repressor;
Gene name	Name=murR;

Comments [?]

FUNCTION	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6- phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator.
PATHWAY	Amino-sugar metabolism; N-acetylmuramate degradation [regulation].
SUBUNIT	Homotetramer.

Keywords [?]

Gene Ontology [?]

GO:0003700; Molecular function:DNA-binding transcription factor activity

GO:0043470; Biological process:regulation of carbohydrate catabolic process

GO:0045892; Biological process:negative regulation of DNA-templated transcription

Cross-references [?]

Features [?]

Additional information [?]