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HAMAP rule MF_02109

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General rule information [?]

Accession MF_02109
Dates 23-FEB-2010 (Created)
19-NOV-2022 (Last updated, Version 11)
Name Cya_synthase
Scope(s) Archaea
Template(s) Q8TKU7 (CYAS_METAC); [ Recover all ]
Triggered by HAMAP; MF_02109 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CYAS
Protein name RecName: Full=Cysteate synthase;
                 Short=Cya synthase;

Comments [?]

FUNCTIONSpecifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
CATALYTIC ACTIVITY Reaction=H(+) + O-phospho-L-serine + sulfite = L-cysteate + phosphate; Xref=Rhea:RHEA:26486, ChEBI:CHEBI:15378, ChEBI:CHEBI:17359, ChEBI:CHEBI:43474, ChEBI:CHEBI:57524, ChEBI:CHEBI:58090; EC=;
COFACTOR Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
PATHWAYCofactor biosynthesis; coenzyme M biosynthesis.
end case
SIMILARITYBelongs to the threonine synthase family. Cysteate synthase subfamily.

Keywords [?]

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Coenzyme M biosynthesis
end case
Pyridoxal phosphate

Gene Ontology [?]

GO:0044686; Molecular function:cysteate synthase activity
GO:0030170; Molecular function:pyridoxal phosphate binding
case <OCellular component:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
GO:0019295; Biological process:coenzyme M biosynthetic process
end case

Cross-references [?]

Pfam PF00291; PALP; 1;

Features [?]

Key From To Description Tag Condition FTGroup
MOD_RES 104 104 /note="N6-(pyridoxal phosphate)lysine" K
BINDING 130 130 /ligand="pyridoxal 5'-phosphate"
From: CYAS_METBU (Q12W15)
Key From To Description Tag Condition FTGroup
BINDING 371 371 /ligand="pyridoxal 5'-phosphate"

Additional information [?]

Size range 412-430 amino acids
Related rules None
Fusion Nter: None Cter: None

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