HAMAP rule MF_02109

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_02109
Accession	MF_02109
Dates	23-FEB-2010 (Created) 08-OCT-2024 (Last updated, Version 14)
Name	Cya_synthase
Scope(s)	Archaea Methanobacteriati
Template(s)	Q8TKU7; [ Recover all ]
Triggered by	HAMAP; MF_02109 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CYAS
Protein name	RecName: Full=Cysteate synthase; Short=CS; Short=Cya synthase; EC=2.5.1.76;

Comments [?]

FUNCTION	Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
CATALYTIC ACTIVITY	Reaction=O-phospho-L-serine + sulfite + H(+) = L-cysteate + phosphate; Xref=Rhea:RHEA:26486, ChEBI:CHEBI:15378, ChEBI:CHEBI:17359, ChEBI:CHEBI:43474, ChEBI:CHEBI:57524, ChEBI:CHEBI:58090; EC=2.5.1.76;
COFACTOR	Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
PATHWAY	Cofactor biosynthesis; coenzyme M biosynthesis.
end case
SUBUNIT	Homotrimer.
SIMILARITY	Belongs to the threonine synthase family. Cysteate synthase subfamily.

Keywords [?]

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Coenzyme M biosynthesis
end case
Pyridoxal phosphate
Transferase

Gene Ontology [?]

GO:0044686; Molecular function:cysteate synthase activity
GO:0030170; Molecular function:pyridoxal phosphate binding
case <OCellular component:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
GO:0019295; Biological process:coenzyme M biosynthetic process
end case

Cross-references [?]

Pfam	PF00291; PALP; 1;

Features [?]

From: CYAS_METAC (Q8TKU7)

Key

From

Description

Tag

Condition

FTGroup

MOD_RES

104

/note="N6-(pyridoxal phosphate)lysine"

BINDING

130

/ligand="pyridoxal 5'-phosphate"
/ligand_id="ChEBI:CHEBI:597326"

From: CYAS_METBU (Q12W15)

Key