HAMAP rule MF_02109

General rule information [?]

Accession	MF_02109
Dates	23-FEB-2010 (Created) 19-NOV-2022 (Last updated, Version 11)

Name	Cya_synthase

Scope

Archaea; Euryarchaeota

Template

Q8TKU7 (CYAS_METAC)

Triggered by

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

CYAS

Protein name

Comments [?]

Function	Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
Catalytic activity	RHEA:26486: H(+) + O-phospho-L-serine + sulfite = L-cysteate + phosphate EC 2.5.1.76
Cofactor	pyridoxal 5'-phosphate

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>

Pathway

Cofactor biosynthesis; coenzyme M biosynthesis.

end case

Subunit	Homotrimer.
Similarity	Belongs to the threonine synthase family. Cysteate synthase subfamily.

Keywords [?]

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>

end case

Gene Ontology [?]

GO:0044686; Molecular function: cysteate synthase activity.
GO:0030170; Molecular function: pyridoxal phosphate binding.

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>

GO:0019295; Biological process: coenzyme M biosynthetic process.

end case

Cross-references [?]

Pfam	PF00291; PALP; 1;

Features [?]

From: CYAS_METAC (Q8TKU7)

Key From To Description Tag Condition FTGroup

MOD_RES 104 104 N6-(pyridoxal phosphate)lysine K

BINDING 130 130 /ligand="pyridoxal 5'-phosphate" /ligand_id="ChEBI:CHEBI:597326 N

From: CYAS_METBU (Q12W15)

BINDING (Optional) 371 371 /ligand="pyridoxal 5'-phosphate" /ligand_id="ChEBI:CHEBI:597326 T

Additional information [?]