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HAMAP rule MF_02109

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General rule information [?]

Accession MF_02109
Dates 23-FEB-2010 (Created)
19-NOV-2022 (Last updated, Version 11)
Name Cya_synthase
Archaea; Euryarchaeota
Template Q8TKU7 (CYAS_METAC)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Cysteate synthase;
Short=Cya synthase;

Comments [?]

Function Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
Catalytic activity RHEA:26486: H(+) + O-phospho-L-serine + sulfite = L-cysteate + phosphate
Cofactor pyridoxal 5'-phosphate
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
Pathway Cofactor biosynthesis; coenzyme M biosynthesis.
end case
Subunit Homotrimer.
Similarity Belongs to the threonine synthase family. Cysteate synthase subfamily.

Keywords [?]

case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
end case

Gene Ontology [?]

GO:0044686; Molecular function: cysteate synthase activity.
GO:0030170; Molecular function: pyridoxal phosphate binding.
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri>
GO:0019295; Biological process: coenzyme M biosynthetic process.
end case

Cross-references [?]

Pfam PF00291; PALP; 1;

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES     104     104       N6-(pyridoxal phosphate)lysine     K  
BINDING     130     130       /ligand="pyridoxal 5'-phosphate" /ligand_id="ChEBI:CHEBI:597326     N  
From: CYAS_METBU (Q12W15)
BINDING (Optional)     371     371       /ligand="pyridoxal 5'-phosphate" /ligand_id="ChEBI:CHEBI:597326     T  

Additional information [?]

Size range 412-430 amino acids
Related rules None
Fusion None