HAMAP rule MF_02109
General rule information
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Accession | MF_02109 |
Dates | 23-FEB-2010 (Created)
19-NOV-2022 (Last updated, Version 11) |
Name | Cya_synthase |
Scope(s) |
Archaea Euryarchaeota |
Template(s) | Q8TKU7 (CYAS_METAC); [ Recover all ] |
Triggered by |
HAMAP; MF_02109 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | CYAS |
Protein name | RecName: Full=Cysteate synthase; Short=CS; Short=Cya synthase; EC=2.5.1.76; |
Comments
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FUNCTION | Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate. |
CATALYTIC ACTIVITY | Reaction=H(+) + O-phospho-L-serine + sulfite = L-cysteate + phosphate; Xref=Rhea:RHEA:26486, ChEBI:CHEBI:15378, ChEBI:CHEBI:17359, ChEBI:CHEBI:43474, ChEBI:CHEBI:57524, ChEBI:CHEBI:58090; EC=2.5.1.76; |
COFACTOR | Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; |
case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
PATHWAY | Cofactor biosynthesis; coenzyme M biosynthesis. |
end case | |
SUBUNIT | Homotrimer. |
SIMILARITY | Belongs to the threonine synthase family. Cysteate synthase subfamily. |
Keywords
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case <OC:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
Coenzyme M biosynthesis | |
end case | |
Pyridoxal phosphate | |
Transferase |
Gene Ontology
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GO:0044686; Molecular function:cysteate synthase activity | |
GO:0030170; Molecular function:pyridoxal phosphate binding | |
case <OCellular component:Methanobacteria> or <OC:Methanococci> or <OC:Methanomicrobia> or <OC:Methanopyri> | |
GO:0019295; Biological process:coenzyme M biosynthetic process | |
end case |
Cross-references
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Pfam | PF00291; PALP; 1; |
Features
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From: CYAS_METAC (Q8TKU7) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
MOD_RES | 104 | 104 | /note="N6-(pyridoxal phosphate)lysine" | K | ||||||||
BINDING | 130 | 130 | /ligand="pyridoxal 5'-phosphate" /ligand_id="ChEBI:CHEBI:597326" |
N | ||||||||
From: CYAS_METBU (Q12W15) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 371 | 371 | /ligand="pyridoxal 5'-phosphate" /ligand_id="ChEBI:CHEBI:597326" |
T |
Additional information
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Size range | 412-430 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |