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Annotation rule MF_02114 |
General rule information
[?]
Accession |
MF_02114 |
Dates |
6-AUG-2010 (Created) 25-AUG-2020 (Last updated, Version 10) |
Scope |
Bacteria; Actinobacteria
Bacteria; Chloroflexi
Bacteria; Proteobacteria
Bacteria; Thermobaculum
Archaea |
Propagated annotation
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Identifier, protein and gene names
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case <OC:Archaea>
Protein name |
RecName:
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Full=2-phospho-L-lactate guanylyltransferase;
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Short=LP guanylyltransferase;
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EC 2.7.7.68;
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else case <OC:Actinobacteria>
Protein name |
RecName:
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Full=Phosphoenolpyruvate guanylyltransferase;
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Short=PEP guanylyltransferase;
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EC 2.7.7.105;
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else case <OC:Proteobacteria>
Protein name |
RecName:
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Full=3-phospho-D-glycerate guanylyltransferase;
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Short=3PG guanylyltransferase;
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EC 2.7.7.106;
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else
Protein name |
RecName:
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Full=Phosphoenolpyruvate guanylyltransferase;
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Short=PEP guanylyltransferase;
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EC 2.7.7.105;
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end case
case <OC:Archaea>
Function |
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. |
else case <OC:Actinobacteria>
Function |
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. |
else case <OC:Proteobacteria>
Function |
Guanylyltransferase that catalyzes the activation of (2R)-3-phosphoglycerate (3PG) as 3-[(R)-glyceryl]-diphospho-5'-guanosine, via the condensation of 3PG with GTP. It is involved in the biosynthesis of a derivative of the hydride carrier cofactor coenzyme F420, 3PG-F420. |
else
Function |
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. |
end case
case <OC:Archaea>
Catalytic activity |
RHEA:63424: (2S)-2-phospholactate + GTP + H(+) = (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate
EC 2.7.7.68
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else case <OC:Actinobacteria>
Catalytic activity |
RHEA:30519: GTP + H(+) + phosphoenolpyruvate = diphosphate + enolpyruvoyl-2-diphospho-5'-guanosine
EC 2.7.7.105
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else case <OC:Proteobacteria>
Catalytic activity |
RHEA:63440: (2R)-3-phosphoglycerate + GTP + H(+) = 3-[(R)-glyceryl]-diphospho-5'-guanosine + diphosphate
EC 2.7.7.106
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else
Catalytic activity |
RHEA:30519: GTP + H(+) + phosphoenolpyruvate = diphosphate + enolpyruvoyl-2-diphospho-5'-guanosine
EC 2.7.7.105
|
end case
Pathway |
Cofactor biosynthesis; coenzyme F420 biosynthesis. |
case <OC:Archaea>
end case
Similarity |
Belongs to the CofC family. |
GO:0070568; Molecular function: guanylyltransferase activity.
GO:0052645; Biological process: F420-0 metabolic process.
case <OC:Actinobacteria>
From: FBID_MYCTU (P9WP83) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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BINDING
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148
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148
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Phosphoenolpyruvate; via amide nitrogen
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T
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BINDING (Optional)
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163
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163
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Phosphoenolpyruvate; via amide nitrogen
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G
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BINDING
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166
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166
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Phosphoenolpyruvate
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S
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end case
Additional information
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Size range |
190-316 amino acids |
Related rules |
None |
Fusion |
None |