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HAMAP rule MF_02125

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General rule information [?]

Accession MF_02125
Dates 28-OCT-2011 (Created)
1-JUN-2023 (Last updated, Version 9)
Name L3_methyltr_PrmB
Scope(s) Bacteria
Pseudomonadota
Template(s) P39199 (PRMB_ECOLI); [ Recover all ]
Triggered by HAMAP; MF_02125 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PRMB
Protein name RecName: Full=Ribosomal protein uL3 glutamine methyltransferase;
                 Short=uL3 MTase;
                 EC=2.1.1.298;
AltName: Full=N5-glutamine methyltransferase PrmB;
Gene name Name=prmB;

Comments [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
FUNCTIONSpecifically methylates ribosomal protein uL3 on 'Gln-150'.
else
FUNCTIONMethylates ribosomal protein uL3 on a specific glutamine residue.
end case
CATALYTIC ACTIVITY Reaction=L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[ribosomal protein uL3] + S- adenosyl-L-homocysteine; Xref=Rhea:RHEA:45020, Rhea:RHEA-COMP:11063, Rhea:RHEA-COMP:11064, ChEBI:CHEBI:15378, ChEBI:CHEBI:30011, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:61891; EC=2.1.1.298;
SIMILARITYBelongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.

Keywords [?]


Gene Ontology [?]

GO:0036009; Molecular function:protein-glutamine N-methyltransferase activity
GO:0018364; Biological process:peptidyl-glutamine methylation

Cross-references [?]

Pfam PF05175; MTS; 1;
NCBIfam TIGR00536; hemK_fam; 1;
NCBIfam TIGR03533; L3_gln_methyl; 1;
PIRSF PIRSF037167; Mtase_YfcB_prd; 1;

Features [?]


Additional information [?]

Size range 297-334 amino acids
Related rules None
Fusion Nter: None Cter: None



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