HAMAP rule MF_02125

General rule information [?]

Accession	MF_02125
Dates	28-OCT-2011 (Created) 2-SEP-2024 (Last updated, Version 10)
Name	L3_methyltr_PrmB
Scope(s)	Bacteria Pseudomonadota
Template(s)	P39199 (PRMB_ECOLI); [ Recover all ]
Triggered by	HAMAP; MF_02125 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	PRMB
Protein name	RecName: Full=Ribosomal protein uL3 glutamine methyltransferase; Short=uL3 MTase; EC=2.1.1.298; AltName: Full=N5-glutamine methyltransferase PrmB;
Gene name	Name=prmB;

Comments [?]

case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella>
FUNCTION	Specifically methylates ribosomal protein uL3 on 'Gln-150'.
else
FUNCTION	Methylates ribosomal protein uL3 on a specific glutamine residue.
end case
CATALYTIC ACTIVITY	Reaction=L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L- homocysteine + H(+); Xref=Rhea:RHEA:45020, Rhea:RHEA-COMP:11063, Rhea:RHEA-COMP:11064, ChEBI:CHEBI:15378, ChEBI:CHEBI:30011, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:61891; EC=2.1.1.298;
SIMILARITY	Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.

Keywords [?]

Gene Ontology [?]

GO:0036009; Molecular function:protein-glutamine N-methyltransferase activity

GO:0018364; Biological process:peptidyl-glutamine methylation

Cross-references [?]

Features [?]

Additional information [?]