HAMAP rule MF_02125
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_02125 |
| Accession | MF_02125 |
| Dates | 28-OCT-2011 (Created)
02-SEP-2024 (Last updated, Version 11) |
| Name | L3_methyltr_PrmB |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | P39199; [ Recover all ] |
| Triggered by |
HAMAP; MF_02125 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | PRMB |
| Protein name | RecName: Full=Ribosomal protein uL3 glutamine methyltransferase; Short=uL3 MTase; EC=2.1.1.298; AltName: Full=N5-glutamine methyltransferase PrmB; |
| Gene name | Name=prmB; |
Comments
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| case <OC:Escherichia> or <OC:Shigella> or <OC:Salmonella> | |
| FUNCTION | Specifically methylates ribosomal protein uL3 on 'Gln-150'. |
| else | |
| FUNCTION | Methylates ribosomal protein uL3 on a specific glutamine residue. |
| end case | |
| CATALYTIC ACTIVITY | Reaction=L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L-methionine = N(5)-methyl-L-glutaminyl-[ribosomal protein uL3] + S-adenosyl-L- homocysteine + H(+); Xref=Rhea:RHEA:45020, Rhea:RHEA-COMP:11063, Rhea:RHEA-COMP:11064, ChEBI:CHEBI:15378, ChEBI:CHEBI:30011, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789, ChEBI:CHEBI:61891; EC=2.1.1.298; |
| SIMILARITY | Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. |
Keywords
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Gene Ontology
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| GO:0036009; Molecular function:protein-glutamine N-methyltransferase activity |
| GO:0018364; Biological process:peptidyl-glutamine methylation |
Cross-references
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| Pfam | PF05175; MTS; 1; |
| NCBIfam | TIGR00536; hemK_fam; 1; |
| NCBIfam | TIGR03533; L3_gln_methyl; 1; |
| PIRSF | PIRSF037167; Mtase_YfcB_prd; 1; |
Features
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Additional information
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| Size range | 297-334 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |