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HAMAP rule MF_02133

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General rule information [?]

Accession MF_02133
Dates 5-SEP-2017 (Created)
6-OCT-2022 (Last updated, Version 5)
Name UBact
Scope
Bacteria
Templates J9ZCN8 (UBACT_LEPFM); A0A0K2G9F6 (UBACT_NITMO); M1YW29 (UBACT_NITG3); S0EX56 (UBACT_CHTCT); B3DVI3 (UBACT_METI4); B9XEI9 (UBACT_PEDPL); A0A0J1BDH3 (UBACT_RHOIS); A0A1F6CTG8 (UBACT_HANXR); A0A1F5UTC9 (UBACT_FRAXR); A0A1G2PK14 (UBACT_TERXR); H5SQ95 (UBACT_ACEAU); A0A0G0MF47 (UBACT_YANXG): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
UBACT
Protein name
RecName: Full=Prokaryotic ubiquitin-like protein UBact;
Gene name
ubact

Comments [?]

case <OC:Planctomycetota>
Function May function as a protein modifier covalently attached to lysine residues of substrate proteins. As this bacterium does not seem to encode proteasome subunits and proteasome ATPase adjacently to UBact, this tagging system may serve another role than targeting the modified proteins for degradation by proteasomes.
else
Function May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes.
end case
case <FTTag:deamidation>
Ptm May be modified by deamidation of its C-terminal glutamine to glutamate by the adjacently encoded deamidase. This could be a prerequisite to the subsequent conjugation, as shown in the other prokaryotic ubiquitin-like protein Pup.
end case
Similarity Belongs to the ubiquitin-like protein UBact family.

Keywords [?]

Isopeptide bond
Ubl conjugation pathway

Gene Ontology [?]

GO:0031386; Molecular function: protein tag.

Features [?]

From: UBACT_NITG3 (M1YW29)
Key     From     To       Description   Tag   Condition   FTGroup
MOD_RES (Optional)     Cter     Cter       Deamidated glutamine   deamidation   Q  
case <FT:1>
CROSSLNK     Cter     Cter       Isoglutamyl lysine isopeptide (Gln-Lys) (interchain with K-? in acceptor proteins)     [Q]  
else
CROSSLNK     Cter     Cter       Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-? in acceptor proteins)     [E]  
end case

Additional information [?]

Size range 56-79 amino acids
Related rules None
Fusion None


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