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HAMAP rule MF_02207

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General rule information [?]

Accession MF_02207
Dates 5-OCT-2018 (Created)
1-JUN-2023 (Last updated, Version 5)
Name MreB
Scope
Archaea
Bacteria
Templates P0A9X4 (MREB_ECOLI); Q01465 (MREB_BACSU); P39751 (MBL_BACSU); P39763 (MREBH_BACSU); A0A0H3C7V4 (MREB_CAUVN): [Recover all]

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MREB
Protein name
RecName: Full=Cell shape-determining protein MreB;
Gene name
mreB

Comments [?]

Function Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
Subunit Forms polymers.
Subcellular location Cytoplasm. Note=Membrane-associated.
Similarity Belongs to the FtsA/MreB family.

Keywords [?]


Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:0008360; Biological process: regulation of cell shape.

Cross-references [?]

Pfam PF06723; MreB_Mbl; 1;
PRINTS PR01652; SHAPEPROTEIN; 1;
NCBIfam TIGR00904; mreB; 1;

Features [?]

From: MREB_CAUVN (A0A0H3C7V4)
Key     From     To       Description   Tag   Condition   FTGroup
BINDING (Optional)     19     21       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     T-A-N  
BINDING (Optional)     165     167       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     [GA]-[GA]-[TS]  
BINDING (Optional)     213     216       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     [ED]-x-[IVLM]-K  
BINDING (Optional)     295     298       /ligand="ATP" /ligand_id="ChEBI:CHEBI:30616     G-[GAS]-[AGS]-L  

Additional information [?]

Size range 270-450 amino acids
Related rules None
Fusion None