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HAMAP rule MF_02209

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General rule information [?]

Accession MF_02209
Dates 23-JAN-2019 (Created)
20-NOV-2019 (Last updated, Version 3)
Name MurL
Scope(s) Bacteria
Template(s) P0DQD8 (MURL_XANOM); C4RJF8 (MURL_MICS3); A4X982 (MURL_SALTO); [ Recover all ]
Triggered by HAMAP; MF_02209 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier MURL
Protein name RecName: Full=UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase;
AltName: Full=UDP-MurNAc-L-Ala-L-Glu epimerase;
Gene name Name=murL;

Comments [?]

FUNCTIONCell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.
CATALYTIC ACTIVITY Reaction=ATP + H2O + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate = AMP + diphosphate + H(+) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl- D-glutamate; Xref=Rhea:RHEA:58812, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:83900, ChEBI:CHEBI:142725, ChEBI:CHEBI:456215; EC=;
PATHWAYCell wall biogenesis; peptidoglycan biosynthesis.
SIMILARITYBelongs to the MurL family.

Keywords [?]

Gene Ontology [?]

GO:0016855; Molecular function:racemase and epimerase activity, acting on amino acids and derivatives
GO:0009252; Biological process:peptidoglycan biosynthetic process
GO:0005737; Cellular component:cytoplasm

Cross-references [?]

Features [?]

Additional information [?]

Size range 400-530 amino acids
Related rules None
Fusion Nter: None Cter: None

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