HAMAP rule MF_02209
General rule information
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| Accession | MF_02209 |
| Dates | 23-JAN-2019 (Created) 20-NOV-2019 (Last updated, Version 3) |
| Name | MurL |
| Scope | Bacteria |
| Templates | P0DQD8 (MURL_XANOM); C4RJF8 (MURL_MICS3); A4X982 (MURL_SALTO): [Recover all] |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate. |
| Catalytic activity | RHEA:58812: ATP + H2O + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate = AMP + diphosphate + H(+) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate
EC 5.1.1.23 |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. |
| Similarity | Belongs to the MurL family. |
Keywords
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Cell cycle
Cell division
Cell shape
Cell wall biogenesis/degradation
Isomerase
Peptidoglycan synthesis
Cell division
Cell shape
Cell wall biogenesis/degradation
Isomerase
Peptidoglycan synthesis
Gene Ontology
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GO:0016855; Molecular function: racemase and epimerase activity, acting on amino acids and derivatives.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005737; Cellular component: cytoplasm.
Additional information
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| Size range | 400-530 amino acids |
| Related rules | None |
| Fusion | None |