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Annotation rule MF_02209
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General rule information [?]

Accession MF_02209
Dates 23-JAN-2019 (Created)
20-NOV-2019 (Last updated, Version 3)
Name MurL
Scope
Bacteria
Templates P0DQD8 (MURL_XANOM); C4RJF8 (MURL_MICS3); A4X982 (MURL_SALTO): [Recover all]
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
MURL
Protein name
RecName: Full=UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate epimerase;
EC 5.1.1.23;
AltName: Full=UDP-MurNAc-L-Ala-L-Glu epimerase;
Gene name
murL

Comments [?]

Function Cell wall formation. Catalyzes epimerization of the terminal L-glutamate in UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate.
Catalytic activity RHEA:58812: ATP + H2O + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate = AMP + diphosphate + H(+) + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate
EC 5.1.1.23
Pathway Cell wall biogenesis; peptidoglycan biosynthesis.
Similarity Belongs to the MurL family.

Keywords [?]

Cell cycle
Cell division
Cell shape
Cell wall biogenesis/degradation
Isomerase
Peptidoglycan synthesis

Gene Ontology [?]

GO:0016855; Molecular function: racemase and epimerase activity, acting on amino acids and derivatives.
GO:0009252; Biological process: peptidoglycan biosynthetic process.
GO:0005737; Cellular component: cytoplasm.

Additional information [?]

Size range 400-530 amino acids
Related rules None
Fusion None


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