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Annotation rule MF_02219 |
Accession | MF_02219 |
Dates | 28-JUN-2019 (Created) 20-NOV-2019 (Last updated, Version 2) |
Name | Type_III_secretin |
Scope | Bacteria |
Templates | Q01244 (SCTC_YEREN); P35672 (SCTC_SALTY); Q04641 (SCTC_SHIFL); D0ZWR9 (SCTC_SALT1): [Recover all] |
Triggered by |
Identifier |
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Protein name |
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Gene name |
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Function | Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane. |
Subunit | The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex. |
Subcellular location | Cell outer membrane. |
Similarity | Belongs to the bacterial secretin family. T3SS SctC subfamily. |
PROSITE | PS00875; T2SP_D; 1; |
Pfam | PF00263; Secretin; 1; |
PF03958; Secretin_N; 2; | |
PRINTS | PR01337; TYPE3OMGPROT; 1; |
TIGRFAMs | TIGR02516; type_III_yscC; 1; |
General | Signal; -; 1; trigger=yes; |
Size range | 460-730 amino acids |
Related rules | None |
Fusion | None |
Comments | A widely accepted unified nomenclature has been proposed for the components of the type III secretion system. Genes are called sct, for secretion and cellular translocation. See Hueck C.J. (PubMed:9618447, 1998) and t3sswiki.science. |