HAMAP rule MF_02219
General rule information
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Accession |
MF_02219 |
Dates |
28-JUN-2019 (Created) 20-NOV-2019 (Last updated, Version 2) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Type 3 secretion system secretin;
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Short=T3SS secretin;
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Flags:
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Precursor;
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Function |
Component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells. Forms a ring-shaped multimeric structure with an apparent central pore in the outer membrane. |
Subunit |
The core secretion machinery of the T3SS is composed of approximately 20 different proteins, including cytoplasmic components, a base, an export apparatus and a needle. This subunit is part of the base, which anchors the injectisome in the bacterial cell envelope. Forms a stable homooligomeric complex. |
Subcellular location |
Cell outer membrane. |
Similarity |
Belongs to the bacterial secretin family. T3SS SctC subfamily. |
GO:0030254; Biological process: protein secretion by the type III secretion system.
GO:0030257; Cellular component: type III protein secretion system complex.
GO:0009279; Cellular component: cell outer membrane.
General |
Signal; -; 1; trigger=yes; |
Additional information
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Size range |
460-730 amino acids |
Related rules |
None |
Fusion |
None |
Comments |
A widely accepted unified nomenclature has been proposed for the components of the type III secretion system. Genes are called sct, for secretion and cellular translocation. See Hueck C.J. (PubMed:9618447, 1998) and t3sswiki.science. |