HAMAP rule MF_02232
General rule information
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| Accession | MF_02232 |
| Dates | 1-OCT-2019 (Created)
26-JAN-2023 (Last updated, Version 5) |
| Name | UbiU |
| Scope(s) |
Bacteria Pseudomonadota |
| Template(s) | P45527 (UBIU_ECOLI); [ Recover all ] |
| Triggered by |
HAMAP; MF_02232 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | UBIU |
| Protein name | RecName: Full=Ubiquinone biosynthesis protein UbiU; |
| Gene name | Name=ubiU; |
Comments
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| FUNCTION | Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiV, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. |
| case <FTGroup:1> | |
| COFACTOR | Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; |
| end case | |
| PATHWAY | Cofactor biosynthesis; ubiquinone biosynthesis. |
| SUBUNIT | Forms an heterodimer with UbiV. |
| SIMILARITY | Belongs to the peptidase U32 family. UbiU subfamily. |
Keywords
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| case <FTGroup:1> | |
| 4Fe-4S | |
| Iron | |
| Iron-sulfur | |
| Metal-binding | |
| end case | |
| Ubiquinone biosynthesis | |
Gene Ontology
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| case <FTGroup:1> | |
| GO:0051539; Molecular function:4 iron, 4 sulfur cluster binding | |
| end case | |
| GO:0006744; Biological process:ubiquinone biosynthetic process | |
Cross-references
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Features
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| From: UBIU_ECOLI (P45527) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 169 | 169 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
C | 1 | |||||||
| BINDING | 176 | 176 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
C | 1 | |||||||
| BINDING | 193 | 193 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
C | 1 | |||||||
| BINDING | 232 | 232 | /ligand="[4Fe-4S] cluster" /ligand_id="ChEBI:CHEBI:49883" |
C | 1 | |||||||
Additional information
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| Size range | 290-400 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |