HAMAP rule MF_02243
General rule information
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| Accession | MF_02243 |
| Dates | 30-JAN-2020 (Created)
19-NOV-2022 (Last updated, Version 3) |
| Name | UxaE |
| Scope(s) |
Bacteria Archaea |
| Template(s) | Q9WYS1 (UXAE_THEMA); [ Recover all ] |
| Triggered by |
HAMAP; MF_02243 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | UXAE |
| Protein name | RecName: Full=Tagaturonate/fructuronate epimerase; Short=D-TagA/D-FruA epimerase; EC=5.1.2.7; |
| Gene name | Name=uxaE; |
Comments
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| FUNCTION | Catalyzes the epimerization of D-tagaturonate (D-TagA) to D- fructuronate (D-FruA). |
| CATALYTIC ACTIVITY | Reaction=keto-D-tagaturonate = keto-D-fructuronate; Xref=Rhea:RHEA:51656, ChEBI:CHEBI:17886, ChEBI:CHEBI:59881; EC=5.1.2.7; |
| COFACTOR | Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; |
| SIMILARITY | Belongs to the UxaE family. |
Keywords
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Gene Ontology
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| GO:0016856; Molecular function:racemase and epimerase activity, acting on hydroxy acids and derivatives |
| GO:0046872; Molecular function:metal ion binding |
Cross-references
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| Pfam | PF16257; UxaE; 1; |
Features
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| From: UXAE_THEMA (Q9WYS1) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| ACT_SITE | 161 | 161 | /note="Proton acceptor" | D | ||||||||
| ACT_SITE | 266 | 266 | /note="Proton donor" | E | ||||||||
| BINDING | 162 | 162 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
H | ||||||||
| BINDING | 308 | 308 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
K | ||||||||
| BINDING | 341 | 341 | /ligand="a divalent metal cation" /ligand_id="ChEBI:CHEBI:60240" |
H | ||||||||
Additional information
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| Size range | 400-550 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |