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HAMAP rule MF_03063

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General rule information [?]

Accession MF_03063
Dates 20-NOV-2013 (Created)
1-JUN-2023 (Last updated, Version 10)
Name EF-G_plantC
Scope(s) Eukaryota
Viridiplantae
Template(s) Q9SI75 (EFGC_ARATH); P34811 (EFGC1_SOYBN); [ Recover all ]
Triggered by HAMAP; MF_03063 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier EFGC
Protein name RecName: Full=Elongation factor G, chloroplastic;
                 Short=cEF-G;

Comments [?]

FUNCTIONChloroplast-localized elongation factor EF-G involved in protein synthesis in plastids. Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl- tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
PATHWAYProtein biosynthesis; polypeptide chain elongation.
SUBCELLULAR LOCATIONPlastid, chloroplast.
case not <AnyFeature:TransitC>
MISCELLANEOUSThis protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
SIMILARITYBelongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

Keywords [?]


Gene Ontology [?]

GO:0003746; Molecular function:translation elongation factor activity
GO:0003924; Molecular function:GTPase activity
GO:0005525; Molecular function:GTP binding
GO:0006414; Biological process:translational elongation
GO:0009507; Cellular component:chloroplast

Cross-references [?]

PROSITE PS00301; G_TR_1; 1;
PROSITE PS51722; G_TR_2; 1;
Pfam PF00679; EFG_C; 1;
Pfam PF14492; EFG_II; 1;
Pfam PF03764; EFG_IV; 1;
Pfam PF00009; GTP_EFTU; 1;
Pfam PF03144; GTP_EFTU_D2; 1;
PRINTS PR00315; ELONGATNFCT; 1;
NCBIfam TIGR00484; EF-G; 1;
NCBIfam TIGR00231; small_GTP; 1;
General TransitC; -; 0-1;

Features [?]

From: EFGC_ARATH (Q9SI75)
Key From To Description Tag Condition FTGroup
BINDING 103 110 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
[AS]-H-[IV]-D-[AS]-G-K-T
BINDING 167 171 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
D-T-P-G-H
BINDING 221 224 /ligand="GTP"
/ligand_id="ChEBI:CHEBI:37565"
N-K-x-D

Additional information [?]

Size range 681-840 amino acids
Related rules MF_03061
Fusion Nter: None Cter: None



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