HAMAP rule MF_03135
General rule information
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| PURL | https://purl.expasy.org/hamap/rule/MF_03135 |
| Accession | MF_03135 |
| Dates | 21-AUG-2012 (Created)
01-JUN-2023 (Last updated, Version 7) |
| Name | EF_Ts_euk |
| Scope(s) |
Eukaryota |
| Template(s) | P43897; [ Recover all ] |
| Triggered by |
case c? <OC:Eukaryota>
HAMAP; MF_00050 (Get profile general information and statistics) end case
|
Propagated annotation
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Identifier, protein and gene names
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| Identifier | EFTS |
| Protein name | RecName: Full=Elongation factor Ts, mitochondrial; Short=EF-Ts; Short=EF-TsMt; |
| case <OC:Vertebrata> or <OC:Amoebozoa> | |
| Gene name | Name=TSFM; |
| else case <OC:Caenorhabditis> | |
| Gene name | Name=tsfm-1; |
| else case <OC:Viridiplantae> | |
| Gene name | Name=EFTS; |
| else case <OC:Fungi> | |
| Gene name | Name=TSF1; |
| end case | |
Comments
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| FUNCTION | Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. |
| SUBCELLULAR LOCATION | Mitochondrion. |
| case not <AnyFeature:TransitM> | |
| MISCELLANEOUS | This protein may be expected to contain an N-terminal transit peptide but none has been predicted. |
| end case | |
| SIMILARITY | Belongs to the EF-Ts family. |
Keywords
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Gene Ontology
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| GO:0003746; Molecular function:translation elongation factor activity |
| GO:0006414; Biological process:translational elongation |
| GO:0005739; Cellular component:mitochondrion |
Cross-references
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| Pfam | PF00889; EF_TS; 1-2; |
| Pfam | PF00627; UBA; 1; |
| NCBIfam | TIGR00116; Tsf; 1; |
| PROSITE | PS01126; EF_TS_1; 1; |
| PROSITE | PS01127; EF_TS_2; 1; |
| General | TransitM; -; 0-1; |
Features
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Additional information
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| Size range | 208-446 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |