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HAMAP rule MF_03135

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General rule information [?]

Accession MF_03135
Dates 22-OCT-2010 (Created)
1-JUN-2023 (Last updated, Version 6)
Name EF_Ts_euk
Scope
Eukaryota
Template P43897 (EFTS_HUMAN)
case <OC:Eukaryota>
Triggered by
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
EFTS
Protein name
RecName: Full=Elongation factor Ts, mitochondrial;
Short=EF-Ts;
Short=EF-TsMt;
case <OC:Vertebrata> or <OC:Amoebozoa>
Gene name
TSFM
else case <OC:Caenorhabditis>
Gene name
tsfm-1
else case <OC:Viridiplantae>
Gene name
EFTS
else case <OC:Fungi>
Gene name
TSF1
end case

Comments [?]

Function Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
Subcellular location Mitochondrion.
case not <AnyFeature:TransitM>
Miscellaneous This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
Similarity Belongs to the EF-Ts family.

Keywords [?]

Elongation factor
Mitochondrion
Protein biosynthesis

Gene Ontology [?]

GO:0003746; Molecular function: translation elongation factor activity.
GO:0006414; Biological process: translational elongation.
GO:0005739; Cellular component: mitochondrion.

Cross-references [?]

Pfam PF00889; EF_TS; 1-2;
PF00627; UBA; 1;
NCBIfam TIGR00116; Tsf; 1;
PROSITE PS01126; EF_TS_1; 1;
PS01127; EF_TS_2; 1;

Computed features [?]

General TransitM; -; 0-1; trigger=yes;

Additional information [?]

Size range 208-446 amino acids
Related rules None
Fusion None


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