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HAMAP rule MF_03149

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General rule information [?]

Accession MF_03149
Dates 18-AUG-2011 (Created)
1-JUN-2023 (Last updated, Version 8)
Name GatC_euk
Scope(s) Eukaryota
Template(s) O43716 (GATC_HUMAN); F4JV80 (GATC_ARATH); [ Recover all ]
Triggered by
case c? <OC:Eukaryota>
HAMAP; MF_00122 (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier GATC
case <OC:Viridiplantae>
Protein name RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit C, chloroplastic/mitochondrial;
                 Short=Glu-AdT subunit C;
                 EC=6.3.5.-;
else
Protein name RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial;
                 Short=Glu-AdT subunit C;
                 EC=6.3.5.-;
end case
case <OC:Vertebrata> or <OC:Viridiplantae>
Gene name Name=GATC;
end case

Comments [?]

case <OC:Viridiplantae>
FUNCTIONAllows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
else
FUNCTIONAllows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
end case
CATALYTIC ACTIVITY Reaction=ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate; Xref=Rhea:RHEA:17521, Rhea:RHEA-COMP:9681, Rhea:RHEA-COMP:9684, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29985, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:58359, ChEBI:CHEBI:78520, ChEBI:CHEBI:78521, ChEBI:CHEBI:456216;
case <OC:Vertebrata>
SUBUNITSubunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (@gn(QRSL1)), B (@gn(GATB)) and C (@gn(GATC)) subunits.
else
SUBUNITSubunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.
end case
case <OC:Viridiplantae>
SUBCELLULAR LOCATIONMitochondrion. Plastid, chloroplast.
else
SUBCELLULAR LOCATIONMitochondrion.
end case
case <OC:Viridiplantae> or not <AnyFeature:TransitM>
MISCELLANEOUSThis protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
SIMILARITYBelongs to the GatC family.

Keywords [?]


Gene Ontology [?]

case <OCellular component:Viridiplantae>
GO:0009507; Cellular component:chloroplast
end case
GO:0005739; Cellular component:mitochondrion
GO:0030956; Cellular component:glutamyl-tRNA(Gln) amidotransferase complex
GO:0050567; Molecular function:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
GO:0016884; Molecular function:carbon-nitrogen ligase activity, with glutamine as amido-N-donor
GO:0070681; Biological process:glutaminyl-tRNAGln biosynthesis via transamidation
GO:0032543; Biological process:mitochondrial translation

Cross-references [?]

Pfam PF02686; Glu-tRNAGln; 1;
NCBIfam TIGR00135; GatC; 1;
General TransitM; -; 0-1;

Features [?]


Additional information [?]

Size range 116-198 amino acids
Related rules None
Fusion Nter: None Cter: None



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