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HAMAP rule MF_03149

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General rule information [?]

Accession MF_03149
Dates 18-AUG-2011 (Created)
1-JUN-2023 (Last updated, Version 8)
Name GatC_euk
Scope
Eukaryota
Templates O43716 (GATC_HUMAN); F4JV80 (GATC_ARATH): [Recover all]
case <OC:Eukaryota>
Triggered by
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
GATC
case <OC:Viridiplantae>
Protein name
RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit C, chloroplastic/mitochondrial;
Short=Glu-AdT subunit C;
EC 6.3.5.-;
else
Protein name
RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial;
Short=Glu-AdT subunit C;
EC 6.3.5.-;
end case
case <OC:Vertebrata> or <OC:Viridiplantae>
Gene name
GATC
end case

Comments [?]

case <OC:Viridiplantae>
Function Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in chloroplasts and mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
else
Function Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
end case
Catalytic activity RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
case <OC:Vertebrata>
Subunit Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (@gn(QRSL1)), B (@gn(GATB)) and C (@gn(GATC)) subunits.
else
Subunit Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A, B and C subunits.
end case
case <OC:Viridiplantae>
Subcellular location Mitochondrion. Plastid, chloroplast.
else
Subcellular location Mitochondrion.
end case
case <OC:Viridiplantae> or not <AnyFeature:TransitM>
Miscellaneous This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
Similarity Belongs to the GatC family.

Keywords [?]

case <OC:Viridiplantae>
Chloroplast
Plastid
end case
Mitochondrion
ATP-binding
Ligase
Nucleotide-binding
Protein biosynthesis

Gene Ontology [?]

case <OC:Viridiplantae>
GO:0009507; Cellular component: chloroplast.
end case
GO:0005739; Cellular component: mitochondrion.
GO:0030956; Cellular component: glutamyl-tRNA(Gln) amidotransferase complex.
GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0016884; Molecular function: carbon-nitrogen ligase activity, with glutamine as amido-N-donor.
GO:0070681; Biological process: glutaminyl-tRNAGln biosynthesis via transamidation.
GO:0032543; Biological process: mitochondrial translation.

Cross-references [?]

Pfam PF02686; Glu-tRNAGln; 1;
NCBIfam TIGR00135; GatC; 1;

Computed features [?]

case not <OC:Viridiplantae>
General TransitM; -; 0-1; trigger=yes;
end case

Additional information [?]

Size range 116-198 amino acids
Related rules None
Fusion None


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