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HAMAP rule MF_03151

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General rule information [?]

Accession MF_03151
Dates 18-AUG-2011 (Created)
20-NOV-2019 (Last updated, Version 6)
Name GatF
Eukaryota; Saccharomycotina
Template P53260 (GATF_YEAST)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial;
Short=Glu-AdT subunit F;
EC 6.3.5.-;
Gene name

Comments [?]

Function Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
Catalytic activity RHEA:17521: ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate
Subunit Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.
Subcellular location Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
case not <AnyFeature:TransitM>
Miscellaneous This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case
Similarity Belongs to the GatF family.

Keywords [?]

Gene Ontology [?]

GO:0005739; Cellular component: mitochondrion.
GO:0030956; Cellular component: glutamyl-tRNA(Gln) amidotransferase complex.
GO:0050567; Molecular function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity.
GO:0016884; Molecular function: carbon-nitrogen ligase activity, with glutamine as amido-N-donor.
GO:0070681; Biological process: glutaminyl-tRNAGln biosynthesis via transamidation.
GO:0032543; Biological process: mitochondrial translation.

Computed features [?]

General TransitM; -; 0-1; trigger=yes;

Additional information [?]

Size range 149-190 amino acids
Related rules None
Fusion None