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| Annotation rule MF_03196 |
General rule information
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| Accession | MF_03196 |
| Dates | 1-SEP-2015 (Created) 20-JUL-2020 (Last updated, Version 7) |
| Name | UbiD_FDC_euk |
| Scope | Eukaryota; Fungi
Eukaryota; Oomycota |
| Templates | Q03034 (FDC1_YEAST); Q9I6N5 (FDC_PSEAE): [Recover all] |
case <OC:Eukaryota>
| Triggered by |
end case
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites. |
| Catalytic activity | RHEA:33227: (E)-4-coumarate + H(+) = 4-hydroxystyrene + CO2
EC 4.1.1.102 |
| RHEA:46920: (E)-cinnamate + H(+) = CO2 + styrene
EC 4.1.1.102 |
|
| RHEA:33807: (E)-ferulate + H(+) = 2-methoxy-4-vinylphenol + CO2
EC 4.1.1.102 |
|
| Cofactor | Mn(2+) |
| prenyl-FMN Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit. |
|
| Subunit | Homodimer. May form higher order oligomers. |
| Subcellular location | Cytoplasm. |
| Similarity | Belongs to the UbiD family. UbiD-like/FDC subfamily. |
Keywords
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Gene Ontology
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GO:0005737; Cellular component: cytoplasm.
GO:0016831; Molecular function: carboxy-lyase activity.
GO:0046281; Biological process: cinnamic acid catabolic process.
GO:0033494; Biological process: ferulate metabolic process.
GO:0016831; Molecular function: carboxy-lyase activity.
GO:0046281; Biological process: cinnamic acid catabolic process.
GO:0033494; Biological process: ferulate metabolic process.
Cross-references
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Features
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| From: FDC1_YEAST (Q03034) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION | 170 | 175 | prenyl-FMN binding | [SN]-W-[SA]-[IV]-x-R | ||||||||
| REGION | 192 | 193 | prenyl-FMN binding | Q-[HD] | ||||||||
| ACT_SITE | 285 | 285 | Proton donor | E | ||||||||
| METAL | 170 | 170 | Manganese | N | ||||||||
| METAL | 193 | 193 | Manganese | H | ||||||||
| METAL | 236 | 236 | Manganese | E | ||||||||
| BINDING | 236 | 236 | prenyl-FMN | E | ||||||||
| BINDING | 394 | 394 | prenyl-FMN | K | ||||||||
Additional information
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| Size range | 494-549 amino acids |
| Related rules | None |
| Fusion | None |