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Annotation rule MF_03196
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General rule information [?]

Accession MF_03196
Dates 1-SEP-2015 (Created)
20-JUL-2020 (Last updated, Version 7)
Name UbiD_FDC_euk
Scope
Eukaryota; Fungi
Eukaryota; Oomycota
Templates Q03034 (FDC1_YEAST); Q9I6N5 (FDC_PSEAE): [Recover all]
case <OC:Eukaryota>
end case


Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
FDC1
Protein name
RecName: Full=Ferulic acid decarboxylase 1;
EC 4.1.1.102;
AltName: Full=Phenacrylate decarboxylase;
Gene name
FDC1

Comments [?]

Function Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites.
Catalytic activity RHEA:33227: (E)-4-coumarate + H(+) = 4-hydroxystyrene + CO2
EC 4.1.1.102
RHEA:46920: (E)-cinnamate + H(+) = CO2 + styrene
EC 4.1.1.102
RHEA:33807: (E)-ferulate + H(+) = 2-methoxy-4-vinylphenol + CO2
EC 4.1.1.102
Cofactor Mn(2+)
prenyl-FMN
Note: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
Subunit Homodimer. May form higher order oligomers.
Subcellular location Cytoplasm.
Similarity Belongs to the UbiD family. UbiD-like/FDC subfamily.

Keywords [?]


Gene Ontology [?]

GO:0005737; Cellular component: cytoplasm.
GO:0016831; Molecular function: carboxy-lyase activity.
GO:0046281; Biological process: cinnamic acid catabolic process.
GO:0033494; Biological process: ferulate metabolic process.

Cross-references [?]

Pfam PF01977; UbiD; 1;
TIGRFAMs TIGR00148; TIGR00148; 1;

Features [?]

From: FDC1_YEAST (Q03034)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     170     175       prenyl-FMN binding     [SN]-W-[SA]-[IV]-x-R  
REGION     192     193       prenyl-FMN binding     Q-[HD]  
ACT_SITE     285     285       Proton donor     E  
METAL     170     170       Manganese     N  
METAL     193     193       Manganese     H  
METAL     236     236       Manganese     E  
BINDING     236     236       prenyl-FMN     E  
BINDING     394     394       prenyl-FMN     K  

Additional information [?]

Size range 494-549 amino acids
Related rules None
Fusion None