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HAMAP rule MF_03197

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General rule information [?]

Accession MF_03197
Dates 1-SEP-2015 (Created)
1-JUN-2023 (Last updated, Version 10)
Name ubiX_pad_euk
Scope(s) Eukaryota
Fungi
Template(s) P33751 (PAD1_YEAST); [ Recover all ]
Triggered by
case c? <OC:Eukaryota>
HAMAP; MF_01984 (Get profile general information and statistics)
end case

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier PAD1
Protein name RecName: Full=Flavin prenyltransferase PAD1, mitochondrial;
                 EC=2.5.1.129;
Gene name Name=PAD1;

Comments [?]

FUNCTIONFlavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for the ferulic acid decarboxylase FDC1. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
CATALYTIC ACTIVITY Reaction=dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2; Xref=Rhea:RHEA:37743, ChEBI:CHEBI:43474, ChEBI:CHEBI:57618, ChEBI:CHEBI:87467, ChEBI:CHEBI:88052; EC=2.5.1.129;
SUBUNITOligomer.
SUBCELLULAR LOCATIONMitochondrion.
SIMILARITYBelongs to the UbiX/PAD1 family.
case not <AnyFeature:TransitM>
MISCELLANEOUSThis protein may be expected to contain an N-terminal transit peptide but none has been predicted.
end case

Keywords [?]


Gene Ontology [?]

GO:0005739; Cellular component:mitochondrion
GO:0004659; Molecular function:prenyltransferase activity

Cross-references [?]

Pfam PF02441; Flavoprotein; 1;
NCBIfam TIGR00421; ubiX_pad; 1;
General TransitM; -; 0-1;

Features [?]

From: PAD1_YEAST (P33751)
Key From To Description Tag Condition FTGroup
BINDING 63 65 /ligand="FMN"
/ligand_id="ChEBI:CHEBI:58210"
G-[AGS]-[ST]
BINDING 140 143 /ligand="FMN"
/ligand_id="ChEBI:CHEBI:58210"
[ST]-x(2)-[ST]
BINDING 89 89 /ligand="FMN"
/ligand_id="ChEBI:CHEBI:58210"
[ST]
BINDING 175 175 /ligand="FMN"
/ligand_id="ChEBI:CHEBI:58210"
R
BINDING 205 205 /ligand="dimethylallyl phosphate"
/ligand_id="ChEBI:CHEBI:88052"
Y
BINDING 221 221 /ligand="dimethylallyl phosphate"
/ligand_id="ChEBI:CHEBI:88052"
[RK]

Additional information [?]

Size range 180-242 amino acids
Related rules MF_01986
Fusion Nter: None Cter: None



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