HAMAP rule MF_03198
General rule information
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Accession |
MF_03198 |
Dates |
7-OCT-2015 (Created) 19-NOV-2022 (Last updated, Version 6) |
Propagated annotation
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Identifier, protein and gene names
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Protein name |
RecName:
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Full=Protein-lysine N-methyltransferase ;
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EC 2.1.1.-;
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AltName:
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Full=Elongation factor methyltransferase 6;
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Function |
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha. |
Subcellular location |
Cytoplasm. |
Similarity |
Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily. |
GO:0005737; Cellular component: cytoplasm.
GO:0016279; Molecular function: protein-lysine N-methyltransferase activity.
GO:0018022; Biological process: peptidyl-lysine methylation.
From: EFM6_YEAST (P53970) |
Key
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From
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To
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Description
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Tag
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Condition
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FTGroup
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BINDING
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87
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89
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/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789
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G-[SA]-G
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BINDING
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51
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51
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/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789
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W
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BINDING
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115
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115
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/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789
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D
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BINDING
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143
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143
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/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789
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W
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BINDING
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169
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169
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/ligand="S-adenosyl-L-methionine" /ligand_id="ChEBI:CHEBI:59789
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[AGS]
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Additional information
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Size range |
221-338 amino acids |
Related rules |
None |
Fusion |
None |