HAMAP rule MF_03224
General rule information
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Accession | MF_03224 |
Dates | 31-MAR-2017 (Created)
20-NOV-2019 (Last updated, Version 4) |
Name | CN_hydrolase |
Scope(s) |
Eukaryota Fungi |
Template(s) | P32963 (CHT_GIBBA); [ Recover all ] |
Triggered by |
HAMAP; MF_03224 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | CHT |
Protein name | RecName: Full=Cyanide hydratase; Short=CHT; EC=4.2.1.66; AltName: Full=Cyanide-degrading nitrilase; AltName: Full=Formamide hydrolyase; |
Comments
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FUNCTION | Catalyzes the hydration of cyanide to formamide. Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants. |
CATALYTIC ACTIVITY | Reaction=formamide = H2O + hydrogen cyanide; Xref=Rhea:RHEA:21720, ChEBI:CHEBI:15377, ChEBI:CHEBI:16397, ChEBI:CHEBI:18407; EC=4.2.1.66; |
INDUCTION | By cyanide. |
SUBUNIT | Oligomer of dimers, forming left-handed helical fibers. |
SIMILARITY | Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. |
Keywords
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Gene Ontology
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GO:0030196; Molecular function:cyanide hydratase activity |
GO:0019500; Biological process:cyanide catabolic process |
Cross-references
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PROSITE | PS50263; CN_HYDROLASE; 1; |
PROSITE | PS00920; NITRIL_CHT_1; 1; |
PROSITE | PS00921; NITRIL_CHT_2; 1; |
Pfam | PF00795; CN_hydrolase; 1; |
Features
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Additional information
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Size range | 332-377 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |