HAMAP rule MF_03224

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_03224
Accession	MF_03224
Dates	31-MAR-2017 (Created) 03-SEP-2024 (Last updated, Version 6)
Name	CN_hydrolase
Scope(s)	Eukaryota Fungi
Template(s)	P32963; [ Recover all ]
Triggered by	HAMAP; MF_03224 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	CHT
Protein name	RecName: Full=Cyanide hydratase; Short=CHT; EC=4.2.1.66; AltName: Full=Cyanide-degrading nitrilase; AltName: Full=Formamide hydrolyase;

Comments [?]

FUNCTION	Catalyzes the hydration of cyanide to formamide. Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants.
CATALYTIC ACTIVITY	Reaction=formamide = hydrogen cyanide + H2O; Xref=Rhea:RHEA:21720, ChEBI:CHEBI:15377, ChEBI:CHEBI:16397, ChEBI:CHEBI:18407; EC=4.2.1.66;
INDUCTION	By cyanide.
SUBUNIT	Oligomer of dimers, forming left-handed helical fibers.
SIMILARITY	Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

Keywords [?]

Gene Ontology [?]

GO:0030196; Molecular function:cyanide hydratase activity

GO:0019500; Biological process:cyanide catabolic process

Cross-references [?]

Features [?]

Additional information [?]