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HAMAP rule MF_03224

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General rule information [?]

Accession MF_03224
Dates 31-MAR-2017 (Created)
20-NOV-2019 (Last updated, Version 4)
Name CN_hydrolase
Scope
Eukaryota; Fungi
Template P32963 (CHT_GIBBA)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CHT
Protein name
RecName: Full=Cyanide hydratase;
Short=CHT;
EC 4.2.1.66;
AltName: Full=Cyanide-degrading nitrilase;
AltName: Full=Formamide hydrolyase;

Comments [?]

Function Catalyzes the hydration of cyanide to formamide. Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants.
Catalytic activity RHEA:21720: formamide = H2O + hydrogen cyanide
EC 4.2.1.66
Induction By cyanide.
Subunit Oligomer of dimers, forming left-handed helical fibers.
Similarity Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

Keywords [?]


Gene Ontology [?]

GO:0030196; Molecular function: cyanide hydratase activity.
GO:0019500; Biological process: cyanide catabolic process.

Cross-references [?]

PROSITE PS50263; CN_HYDROLASE; 1; trigger=PRU00054;
PS00920; NITRIL_CHT_1; 1;
PS00921; NITRIL_CHT_2; 1;
Pfam PF00795; CN_hydrolase; 1;

Additional information [?]

Size range 332-377 amino acids
Related rules None
Fusion None