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HAMAP rule MF_03224

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General rule information [?]

Accession MF_03224
Dates 31-MAR-2017 (Created)
20-NOV-2019 (Last updated, Version 4)
Name CN_hydrolase
Scope(s) Eukaryota
Fungi
Template(s) P32963 (CHT_GIBBA); [ Recover all ]
Triggered by HAMAP; MF_03224 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CHT
Protein name RecName: Full=Cyanide hydratase;
                 Short=CHT;
                 EC=4.2.1.66;
AltName: Full=Cyanide-degrading nitrilase;
AltName: Full=Formamide hydrolyase;

Comments [?]

FUNCTIONCatalyzes the hydration of cyanide to formamide. Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants.
CATALYTIC ACTIVITY Reaction=formamide = H2O + hydrogen cyanide; Xref=Rhea:RHEA:21720, ChEBI:CHEBI:15377, ChEBI:CHEBI:16397, ChEBI:CHEBI:18407; EC=4.2.1.66;
INDUCTIONBy cyanide.
SUBUNITOligomer of dimers, forming left-handed helical fibers.
SIMILARITYBelongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

Keywords [?]


Gene Ontology [?]

GO:0030196; Molecular function:cyanide hydratase activity
GO:0019500; Biological process:cyanide catabolic process

Cross-references [?]

PROSITE PS50263; CN_HYDROLASE; 1;
PROSITE PS00920; NITRIL_CHT_1; 1;
PROSITE PS00921; NITRIL_CHT_2; 1;
Pfam PF00795; CN_hydrolase; 1;

Features [?]


Additional information [?]

Size range 332-377 amino acids
Related rules None
Fusion Nter: None Cter: None



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