HAMAP logo

HAMAP rule MF_03228

Send feedback

General rule information [?]

Accession MF_03228
Dates 17-JUN-2019 (Created)
19-NOV-2022 (Last updated, Version 6)
Name But_CoA_trans
Scope(s) Bacteria
Template(s) Q0AVM5 (BCT_SYNWW); G2SYC0 (BCACT_ROSHA); [ Recover all ]
Triggered by HAMAP; MF_03228 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier BCT
Protein name RecName: Full=Probable butyrate:acetyl-CoA coenzyme A-transferase;
                 Short=Butyrate CoA-transferase;
                 EC=2.8.3.-;

Comments [?]

FUNCTIONCoenzyme A-transferase that converts butyrate to butyryl-CoA.
CATALYTIC ACTIVITY Reaction=acetyl-CoA + butanoate = acetate + butanoyl-CoA; Xref=Rhea:RHEA:30071, ChEBI:CHEBI:17968, ChEBI:CHEBI:30089, ChEBI:CHEBI:57288, ChEBI:CHEBI:57371;
PATHWAYLipid metabolism; butanoate metabolism.
SUBCELLULAR LOCATIONCytoplasm.
SIMILARITYBelongs to the acetyl-CoA hydrolase/transferase family.

Keywords [?]


Gene Ontology [?]

GO:0016740; Molecular function:transferase activity
GO:0006084; Biological process:acetyl-CoA metabolic process
GO:0019605; Biological process:butyrate metabolic process

Cross-references [?]

Pfam PF13336; AcetylCoA_hyd_C; 1;
Pfam PF02550; AcetylCoA_hydro; 1;

Features [?]

From: BCT_SYNWW (Q0AVM5)
Key From To Description Tag Condition FTGroup
BINDING 220 224 /ligand="CoA"
/ligand_id="ChEBI:CHEBI:57287"
G-x-G-x-x
ACT_SITE 245 245 /note="5-glutamyl coenzyme A thioester intermediate" E
BINDING 320 320 /ligand="CoA"
/ligand_id="ChEBI:CHEBI:57287"
[ILVM]
BINDING 343 343 /ligand="CoA"
/ligand_id="ChEBI:CHEBI:57287"
G

Additional information [?]

Size range 437-460 amino acids
Related rules MF_03227
Fusion Nter: None Cter: None



View rule in raw text format (no links)