HAMAP rule MF_03228
General rule information
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Accession | MF_03228 |
Dates | 17-JUN-2019 (Created)
19-NOV-2022 (Last updated, Version 6) |
Name | But_CoA_trans |
Scope(s) |
Bacteria |
Template(s) | Q0AVM5 (BCT_SYNWW); G2SYC0 (BCACT_ROSHA); [ Recover all ] |
Triggered by |
HAMAP; MF_03228 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | BCT |
Protein name | RecName: Full=Probable butyrate:acetyl-CoA coenzyme A-transferase; Short=Butyrate CoA-transferase; EC=2.8.3.-; |
Comments
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FUNCTION | Coenzyme A-transferase that converts butyrate to butyryl-CoA. |
CATALYTIC ACTIVITY | Reaction=acetyl-CoA + butanoate = acetate + butanoyl-CoA; Xref=Rhea:RHEA:30071, ChEBI:CHEBI:17968, ChEBI:CHEBI:30089, ChEBI:CHEBI:57288, ChEBI:CHEBI:57371; |
PATHWAY | Lipid metabolism; butanoate metabolism. |
SUBCELLULAR LOCATION | Cytoplasm. |
SIMILARITY | Belongs to the acetyl-CoA hydrolase/transferase family. |
Keywords
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Gene Ontology
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GO:0016740; Molecular function:transferase activity |
GO:0006084; Biological process:acetyl-CoA metabolic process |
GO:0019605; Biological process:butyrate metabolic process |
Cross-references
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Features
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From: BCT_SYNWW (Q0AVM5) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
BINDING | 220 | 224 | /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287" |
G-x-G-x-x | ||||||||
ACT_SITE | 245 | 245 | /note="5-glutamyl coenzyme A thioester intermediate" | E | ||||||||
BINDING | 320 | 320 | /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287" |
[ILVM] | ||||||||
BINDING | 343 | 343 | /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287" |
G |
Additional information
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Size range | 437-460 amino acids |
Related rules |
MF_03227 |
Fusion | Nter: None Cter: None |