HAMAP rule MF_03228
General rule information
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| Accession | MF_03228 |
| Dates | 17-JUN-2019 (Created)
3-SEP-2024 (Last updated, Version 7) |
| Name | But_CoA_trans |
| Scope(s) |
Bacteria |
| Template(s) | Q0AVM5 (BCT_SYNWW); G2SYC0 (BCACT_ROSHA); [ Recover all ] |
| Triggered by |
HAMAP; MF_03228 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | BCT |
| Protein name | RecName: Full=Probable butyrate:acetyl-CoA coenzyme A-transferase; Short=Butyrate CoA-transferase; EC=2.8.3.-; |
Comments
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| FUNCTION | Coenzyme A-transferase that converts butyrate to butyryl-CoA. |
| CATALYTIC ACTIVITY | Reaction=butanoate + acetyl-CoA = butanoyl-CoA + acetate; Xref=Rhea:RHEA:30071, ChEBI:CHEBI:17968, ChEBI:CHEBI:30089, ChEBI:CHEBI:57288, ChEBI:CHEBI:57371; |
| PATHWAY | Lipid metabolism; butanoate metabolism. |
| SUBCELLULAR LOCATION | Cytoplasm. |
| SIMILARITY | Belongs to the acetyl-CoA hydrolase/transferase family. |
Keywords
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Gene Ontology
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| GO:0016740; Molecular function:transferase activity |
| GO:0006084; Biological process:acetyl-CoA metabolic process |
| GO:0019605; Biological process:butyrate metabolic process |
Cross-references
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Features
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| From: BCT_SYNWW (Q0AVM5) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| BINDING | 220 | 224 | /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287" |
G-x-G-x-x | ||||||||
| ACT_SITE | 245 | 245 | /note="5-glutamyl coenzyme A thioester intermediate" | E | ||||||||
| BINDING | 320 | 320 | /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287" |
[ILVM] | ||||||||
| BINDING | 343 | 343 | /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287" |
G | ||||||||
Additional information
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| Size range | 437-460 amino acids |
| Related rules |
MF_03227 |
| Fusion | Nter: None Cter: None |