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HAMAP rule MF_03228

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General rule information [?]

Accession MF_03228
Dates 17-JUN-2019 (Created)
19-NOV-2022 (Last updated, Version 6)
Name But_CoA_trans
Templates Q0AVM5 (BCT_SYNWW); G2SYC0 (BCACT_ROSHA): [Recover all]

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Probable butyrate:acetyl-CoA coenzyme A-transferase;
Short=Butyrate CoA-transferase;
EC 2.8.3.-;

Comments [?]

Function Coenzyme A-transferase that converts butyrate to butyryl-CoA.
Catalytic activity RHEA:30071: acetyl-CoA + butanoate = acetate + butanoyl-CoA
Pathway Lipid metabolism; butanoate metabolism.
Subcellular location Cytoplasm.
Similarity Belongs to the acetyl-CoA hydrolase/transferase family.

Keywords [?]

Gene Ontology [?]

GO:0016740; Molecular function: transferase activity.
GO:0006084; Biological process: acetyl-CoA metabolic process.
GO:0019605; Biological process: butyrate metabolic process.

Cross-references [?]

Pfam PF13336; AcetylCoA_hyd_C; 1;
PF02550; AcetylCoA_hydro; 1;

Features [?]

Key     From     To       Description   Tag   Condition   FTGroup
BINDING     220     224       /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287     G-x-G-x-x  
ACT_SITE     245     245       5-glutamyl coenzyme A thioester intermediate     E  
BINDING     320     320       /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287     [ILVM]  
BINDING     343     343       /ligand="CoA" /ligand_id="ChEBI:CHEBI:57287     G  

Additional information [?]

Size range 437-460 amino acids
Related rules MF_03227 (BCACT supersedes the current rule)
Fusion None