HAMAP rule MF_04018
General rule information
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| Accession | MF_04018 |
| Dates | 4-APR-2016 (Created) 20-NOV-2019 (Last updated, Version 4) |
| Name | HSV_TRX1 |
| Scope | Viruses; Herpesviridae |
| Template | P32888 (TRX1_HHV11) |
| Triggered by |
Propagated annotation
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Identifier, protein and gene names
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| Identifier |
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| Protein name |
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| Gene name |
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Comments
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| Function | Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly. |
| Subunit | Interacts with TRX2, MCP and capsid vertex component 2/CVC2. |
| Subcellular location | Virion. Host nucleus. |
| Similarity | Belongs to the herpesviridae TRX1 protein family. |
Keywords
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Gene Ontology
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GO:0042025; Cellular component: host cell nucleus.
GO:0019028; Cellular component: viral capsid.
GO:0003677; Molecular function: DNA binding.
GO:0019069; Biological process: viral capsid assembly.
GO:0019028; Cellular component: viral capsid.
GO:0003677; Molecular function: DNA binding.
GO:0019069; Biological process: viral capsid assembly.
Cross-references
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| Pfam | PF03327; Herpes_VP19C; 1; |
Additional information
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| Size range | 286-486 amino acids |
| Related rules | None |
| Fusion | None |