HAMAP rule MF_04018
General rule information
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Accession | MF_04018 |
Dates | 4-APR-2016 (Created)
20-NOV-2019 (Last updated, Version 4) |
Name | HSV_TRX1 |
Scope(s) |
Viruses Herpesviridae |
Template(s) | P32888 (TRX1_HHV11); [ Recover all ] |
Triggered by |
HAMAP; MF_04018 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | TRX1 |
Protein name | RecName: Full=Triplex capsid protein 1; |
Gene name | Name=TRX1; |
Comments
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FUNCTION | Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly. |
SUBUNIT | Interacts with TRX2, MCP and capsid vertex component 2/CVC2. |
SUBCELLULAR LOCATION | Virion. Host nucleus. |
SIMILARITY | Belongs to the herpesviridae TRX1 protein family. |
Keywords
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Gene Ontology
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GO:0042025; Cellular component:host cell nucleus |
GO:0019028; Cellular component:viral capsid |
GO:0003677; Molecular function:DNA binding |
GO:0019069; Biological process:viral capsid assembly |
Cross-references
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Pfam | PF03327; Herpes_VP19C; 1; |
Features
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Additional information
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Size range | 286-486 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |