HAMAP rule MF_04018

General rule information [?]

PURL	https://purl.expasy.org/hamap/rule/MF_04018
Accession	MF_04018
Dates	04-APR-2016 (Created) 20-NOV-2019 (Last updated, Version 5)
Name	HSV_TRX1
Scope(s)	Viruses Herpesviridae
Template(s)	P32888; [ Recover all ]
Triggered by	HAMAP; MF_04018 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier	TRX1
Protein name	RecName: Full=Triplex capsid protein 1;
Gene name	Name=TRX1;

Comments [?]

FUNCTION	Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
SUBUNIT	Interacts with TRX2, MCP and capsid vertex component 2/CVC2.
SUBCELLULAR LOCATION	Virion. Host nucleus.
SIMILARITY	Belongs to the herpesviridae TRX1 protein family.

Keywords [?]

Gene Ontology [?]

GO:0042025; Cellular component:host cell nucleus

GO:0019028; Cellular component:viral capsid

GO:0003677; Molecular function:DNA binding

GO:0019069; Biological process:viral capsid assembly

Cross-references [?]

Pfam	PF03327; Herpes_VP19C; 1;

Features [?]

Additional information [?]