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HAMAP rule MF_04018

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General rule information [?]

Accession MF_04018
Dates 4-APR-2016 (Created)
20-NOV-2019 (Last updated, Version 4)
Viruses; Herpesviridae
Template P32888 (TRX1_HHV11)

Propagated annotation [?]

Identifier, protein and gene names [?]

Protein name
RecName: Full=Triplex capsid protein 1;
Gene name

Comments [?]

Function Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
Subunit Interacts with TRX2, MCP and capsid vertex component 2/CVC2.
Subcellular location Virion. Host nucleus.
Similarity Belongs to the herpesviridae TRX1 protein family.

Keywords [?]

Gene Ontology [?]

GO:0042025; Cellular component: host cell nucleus.
GO:0019028; Cellular component: viral capsid.
GO:0003677; Molecular function: DNA binding.
GO:0019069; Biological process: viral capsid assembly.

Cross-references [?]

Pfam PF03327; Herpes_VP19C; 1;

Additional information [?]

Size range 286-486 amino acids
Related rules None
Fusion None