HAMAP rule MF_04019

Accession	MF_04019
Dates	4-APR-2016 (Created) 20-NOV-2019 (Last updated, Version 5)

Name

HSV_TRX2

Scope

Viruses; Herpesviridae

Template

P10202 (TRX2_HHV11)

Triggered by

HAMAP; MF_04019 (Get profile general information and statistics)

Identifier

TRX2

Protein name

RecName: Full=Triplex capsid protein 2;

Gene name

TRX2

Function	Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
Subunit	Interacts with TRX1 and major capisd protein/MCP.
Subcellular location	Virion. Host nucleus.
Similarity	Belongs to the herpesviridae TRX2 protein family.

Capsid protein
Host nucleus
Virion

GO:0042025; Cellular component: host cell nucleus.
GO:0019028; Cellular component: viral capsid.
GO:0019069; Biological process: viral capsid assembly.

Pfam	PF01802; Herpes_V23; 1;

Size range	292-321 amino acids
Related rules	None
Fusion	None

View rule in raw text format (no links)