HAMAP rule MF_04025

General rule information [?]

Accession	MF_04025
Dates	22-APR-2016 (Created) 20-NOV-2019 (Last updated, Version 4)

Name

HSV_CVC2

Scope

Viruses; Herpesviridae

Template

P10209 (CVC2_HHV11)

Triggered by

HAMAP; MF_04025 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier

CVC2

Protein name

RecName:

Full=Capsid vertex component 2;

Gene name

CVC2

Comments [?]

Function	Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
Subunit	Heterodimerizes with CVC1. Interacts with major capsid protein/MCP and triplex capsid protein 1/TRX1 at the pentamer vertices. Interacts with the large tegument protein/LTP.
Subcellular location	Virion. Host nucleus.
Similarity	Belongs to the herpesviridae CVC2 protein family.

Keywords [?]

Capsid protein
Host nucleus
Host-virus interaction
Viral genome packaging
Viral penetration into host nucleus
Virion
Virus entry into host cell
Viral release from host cell

Gene Ontology [?]

GO:0042025; Cellular component: host cell nucleus.
GO:0019028; Cellular component: viral capsid.
GO:0046718; Biological process: viral entry into host cell.
GO:0019072; Biological process: viral genome packaging.
GO:0075732; Biological process: viral penetration into host nucleus.
GO:0019076; Biological process: viral release from host cell.

Cross-references [?]

Pfam	PF01499; Herpes_UL25; 1;

Features [?]

From: CVC2_HHV11 (P10209)

Key From To Description Tag Condition FTGroup

REGION Nter 50 Interaction with major capsid protein/MCP

Additional information [?]

Size range	543-642 amino acids
Related rules	None
Fusion	None

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