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Annotation rule MF_04025
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General rule information [?]

Accession MF_04025
Dates 22-APR-2016 (Created)
20-NOV-2019 (Last updated, Version 4)
Name HSV_CVC2
Scope
Viruses; Herpesviridae
Template P10209 (CVC2_HHV11)
Triggered by

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
CVC2
Protein name
RecName: Full=Capsid vertex component 2;
Gene name
CVC2

Comments [?]

Function Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
Subunit Heterodimerizes with CVC1. Interacts with major capsid protein/MCP and triplex capsid protein 1/TRX1 at the pentamer vertices. Interacts with the large tegument protein/LTP.
Subcellular location Virion. Host nucleus.
Similarity Belongs to the herpesviridae CVC2 protein family.

Keywords [?]

Capsid protein
Host nucleus
Host-virus interaction
Viral genome packaging
Viral penetration into host nucleus
Virion
Virus entry into host cell
Viral release from host cell

Gene Ontology [?]

GO:0042025; Cellular component: host cell nucleus.
GO:0019028; Cellular component: viral capsid.
GO:0046718; Biological process: viral entry into host cell.
GO:0019072; Biological process: viral genome packaging.
GO:0075732; Biological process: viral penetration into host nucleus.
GO:0019076; Biological process: viral release from host cell.

Cross-references [?]

Pfam PF01499; Herpes_UL25; 1;

Features [?]

From: CVC2_HHV11 (P10209)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     Nter     50       Interaction with major capsid protein/MCP        

Additional information [?]

Size range 543-642 amino acids
Related rules None
Fusion None


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