HAMAP logo
Due to maintenance work, this service will be unavailable on Monday between 06:00 until 06:30 CEST. Apologies for the inconvenience.

HAMAP rule MF_04025

Send feedback

General rule information [?]

Accession MF_04025
Dates 22-APR-2016 (Created)
1-MAR-2024 (Last updated, Version 5)
Name HSV_CVC2
Scope(s) Viruses
Herpesviridae
Template(s) P10209 (CVC2_HHV11); [ Recover all ]
Triggered by HAMAP; MF_04025 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier CVC2
Protein name RecName: Full=Capsid vertex component 2;
Gene name Name=CVC2;

Comments [?]

FUNCTIONCapsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP.
SUBUNITHeterodimerizes with CVC1. Interacts with major capsid protein/MCP and triplex capsid protein 1/TRX1 at the pentamer vertices. Interacts with the large tegument protein/LTP.
SUBCELLULAR LOCATIONVirion. Host nucleus.
SIMILARITYBelongs to the herpesviridae CVC2 protein family.

Keywords [?]


Gene Ontology [?]

GO:0042025; Cellular component:host cell nucleus
GO:0019028; Cellular component:viral capsid
GO:0046718; Biological process:symbiont entry into host cell
GO:0019072; Biological process:viral genome packaging
GO:0075732; Biological process:viral penetration into host nucleus
GO:0019076; Biological process:viral release from host cell

Cross-references [?]

Pfam PF01499; Herpes_UL25; 1;

Features [?]

From: CVC2_HHV11 (P10209)
Key From To Description Tag Condition FTGroup
REGION Nter 50 /note="Interaction with major capsid protein/MCP"

Additional information [?]

Size range 543-642 amino acids
Related rules None
Fusion Nter: None Cter: None



View rule in raw text format (no links)