HAMAP rule MF_04025
General rule information
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Accession | MF_04025 |
Dates | 22-APR-2016 (Created)
20-NOV-2019 (Last updated, Version 4) |
Name | HSV_CVC2 |
Scope(s) |
Viruses Herpesviridae |
Template(s) | P10209 (CVC2_HHV11); [ Recover all ] |
Triggered by |
HAMAP; MF_04025 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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Identifier | CVC2 |
Protein name | RecName: Full=Capsid vertex component 2; |
Gene name | Name=CVC2; |
Comments
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FUNCTION | Capsid vertex-specific component that plays a role during viral DNA encapsidation, assuring correct genome cleavage and presumably stabilizing capsids that contain full-length viral genomes. Participates in the interaction between the capsid and the tegument through interaction with the large tegument protein/LTP. |
SUBUNIT | Heterodimerizes with CVC1. Interacts with major capsid protein/MCP and triplex capsid protein 1/TRX1 at the pentamer vertices. Interacts with the large tegument protein/LTP. |
SUBCELLULAR LOCATION | Virion. Host nucleus. |
SIMILARITY | Belongs to the herpesviridae CVC2 protein family. |
Keywords
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Capsid protein |
Host nucleus |
Host-virus interaction |
Viral genome packaging |
Viral penetration into host nucleus |
Virion |
Virus entry into host cell |
Viral release from host cell |
Gene Ontology
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GO:0042025; Cellular component:host cell nucleus |
GO:0019028; Cellular component:viral capsid |
GO:0046718; Biological process:viral entry into host cell |
GO:0019072; Biological process:viral genome packaging |
GO:0075732; Biological process:viral penetration into host nucleus |
GO:0019076; Biological process:viral release from host cell |
Cross-references
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Pfam | PF01499; Herpes_UL25; 1; |
Features
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From: CVC2_HHV11 (P10209) | ||||||||||||
Key | From | To | Description | Tag | Condition | FTGroup | ||||||
REGION | Nter | 50 | /note="Interaction with major capsid protein/MCP" |
Additional information
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Size range | 543-642 amino acids |
Related rules |
None |
Fusion | Nter: None Cter: None |