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HAMAP rule MF_04043

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General rule information [?]

Accession MF_04043
Dates 29-SEP-2016 (Created)
20-NOV-2019 (Last updated, Version 5)
Name HSV_ITP
Scope
Viruses; Herpesviridae
Template P10221 (ITP_HHV11)

Propagated annotation [?]


Identifier, protein and gene names [?]

Identifier
ITP
Protein name
RecName: Full=Inner tegument protein;

Comments [?]

Function Plays an essential role in cytoplasmic secondary envelopment during viral egress. Interacts with the capsid via the large tegument protein/LTP and participates in its transport to the host trans-Golgi network (TGN) where secondary envelopment occurs. Modulates tegumentation and capsid accumulation at the viral assembly complex.
Subunit Interacts (via C-teminus) with the large tegument protein/LTP (via N-terminus).
Subcellular location Virion tegument. Host cytoplasm. Host nucleus. Host Golgi apparatus, host trans-Golgi network.
Similarity Belongs to the herpesviridae inner tegument protein family.

Keywords [?]


Gene Ontology [?]

GO:0019033; Cellular component: viral tegument.
GO:0042802; Molecular function: identical protein binding.
GO:0039701; Biological process: microtubule-dependent intracellular transport of viral material towards cell periphery.
GO:0019068; Biological process: virion assembly.

Cross-references [?]

Pfam PF03970; Herpes_UL37_1; 1;
PF04523; Herpes_U30; 1;

Features [?]

From: ITP_HHV11 (P10221)
Key     From     To       Description   Tag   Condition   FTGroup
REGION     568     Cter       Interaction with large tegument protein        

Additional information [?]

Size range 899-1240 amino acids
Related rules None
Fusion None