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HAMAP rule MF_04043

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General rule information [?]

Accession MF_04043
Dates 29-SEP-2016 (Created)
20-NOV-2019 (Last updated, Version 5)
Scope(s) Viruses
Template(s) P10221 (ITP_HHV11); [ Recover all ]
Triggered by HAMAP; MF_04043 (Get profile general information and statistics)

Propagated annotation [?]

Identifier, protein and gene names [?]

Identifier ITP
Protein name RecName: Full=Inner tegument protein;

Comments [?]

FUNCTIONPlays an essential role in cytoplasmic secondary envelopment during viral egress. Interacts with the capsid via the large tegument protein/LTP and participates in its transport to the host trans-Golgi network (TGN) where secondary envelopment occurs. Modulates tegumentation and capsid accumulation at the viral assembly complex.
SUBUNITInteracts (via C-teminus) with the large tegument protein/LTP (via N-terminus).
SUBCELLULAR LOCATIONVirion tegument. Host cytoplasm. Host nucleus. Host Golgi apparatus, host trans-Golgi network.
SIMILARITYBelongs to the herpesviridae inner tegument protein family.

Keywords [?]

Gene Ontology [?]

GO:0019033; Cellular component:viral tegument
GO:0042802; Molecular function:identical protein binding
GO:0039701; Biological process:microtubule-dependent intracellular transport of viral material towards cell periphery
GO:0019068; Biological process:virion assembly

Cross-references [?]

Pfam PF03970; Herpes_UL37_1; 1;
Pfam PF04523; Herpes_U30; 1;

Features [?]

From: ITP_HHV11 (P10221)
Key From To Description Tag Condition FTGroup
REGION 568 Cter /note="Interaction with large tegument protein"

Additional information [?]

Size range 899-1240 amino acids
Related rules None
Fusion Nter: None Cter: None

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