HAMAP rule MF_04043
General rule information
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| Accession | MF_04043 |
| Dates | 29-SEP-2016 (Created)
20-NOV-2019 (Last updated, Version 5) |
| Name | HSV_ITP |
| Scope(s) |
Viruses Herpesviridae |
| Template(s) | P10221 (ITP_HHV11); [ Recover all ] |
| Triggered by |
HAMAP; MF_04043 (Get profile general information and statistics) |
Propagated annotation
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Identifier, protein and gene names
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| Identifier | ITP |
| Protein name | RecName: Full=Inner tegument protein; |
Comments
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| FUNCTION | Plays an essential role in cytoplasmic secondary envelopment during viral egress. Interacts with the capsid via the large tegument protein/LTP and participates in its transport to the host trans-Golgi network (TGN) where secondary envelopment occurs. Modulates tegumentation and capsid accumulation at the viral assembly complex. |
| SUBUNIT | Interacts (via C-teminus) with the large tegument protein/LTP (via N-terminus). |
| SUBCELLULAR LOCATION | Virion tegument. Host cytoplasm. Host nucleus. Host Golgi apparatus, host trans-Golgi network. |
| SIMILARITY | Belongs to the herpesviridae inner tegument protein family. |
Keywords
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Gene Ontology
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| GO:0019033; Cellular component:viral tegument |
| GO:0042802; Molecular function:identical protein binding |
| GO:0039701; Biological process:microtubule-dependent intracellular transport of viral material towards cell periphery |
| GO:0019068; Biological process:virion assembly |
Cross-references
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Features
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| From: ITP_HHV11 (P10221) | ||||||||||||
| Key | From | To | Description | Tag | Condition | FTGroup | ||||||
| REGION | 568 | Cter | /note="Interaction with large tegument protein" | |||||||||
Additional information
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| Size range | 899-1240 amino acids |
| Related rules |
None |
| Fusion | Nter: None Cter: None |